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"Sujin Jang"

Study protocol

Cardiovascular

SEALONE (Safety and Efficacy of Coronary Computed Tomography Angiography with Low Dose in Patients Visiting Emergency Room) trial: study protocol for a randomized controlled trial
Joonghee Kim, Joon-Won Kang, Kyuseok Kim, Sang Il Choi, Eun Ju Chun, Yeo Goon Kim, Won Young Kim, Dong Woo Seo, Jonghwan Shin, Huijai Lee, Kwang-Nam Jin, Soyeon Ahn, Seung Sik Hwang, Kwang Pyo Kim, Ru-Bi Jeong, Sang Ook Ha, Byungho Choi, Chang-Hwan Yoon, Jung-Won Suh, Hack-Lyoung Kim, Ju Kyoung Kim, Sujin Jang, Ji Seon Seo
Clin Exp Emerg Med 2017;4(4):208-213.   Published online December 30, 2017
DOI: https://doi.org/10.15441/ceem.17.245

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SEALONE (Safety and Efficacy of Coronary Computed Tomography Angiography with Low Dose in Patients Visiting Emergency Room) trial: study protocol for a randomized controlled trial
Clin Exp Emerg Med. 2017;4(4):208-213.   Published online December 30, 2017
DOI: https://doi.org/10.15441/ceem.17.245
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SEALONE (Safety and Efficacy of Coronary Computed Tomography Angiography with Low Dose in Patients Visiting Emergency Room) trial: study protocol for a randomized controlled trial
Clin Exp Emerg Med. 2017;4(4):208-213.   Published online December 30, 2017
DOI: https://doi.org/10.15441/ceem.17.245
Close
Objective
Chest pain is one of the most common complaints in the emergency department (ED). Cardiac computed tomography angiography (CCTA) is a frequently used tool for the early triage of patients with low- to intermediate-risk acute chest pain. We present a study protocol for a multicenter prospective randomized controlled clinical trial testing the hypothesis that a low-dose CCTA protocol using prospective electrocardiogram (ECG)-triggering and limited-scan range can provide sufficient diagnostic safety for early triage of patients with acute chest pain.
Methods
The trial will include 681 younger adult (aged 20 to 55) patients visiting EDs of three academic hospitals for acute chest pain or equivalent symptoms who require further evaluation to rule out acute coronary syndrome. Participants will be randomly allocated to either low-dose or conventional CCTA protocol at a 2:1 ratio. The low-dose group will undergo CCTA with prospective ECG-triggering and restricted scan range from sub-carina to heart base. The conventional protocol group will undergo CCTA with retrospective ECG-gating covering the entire chest. Patient disposition is determined based on computed tomography findings and clinical progression and all patients are followed for a month. The primary objective is to prove that the chance of experiencing any hard event within 30 days after a negative low-dose CCTA is less than 1%. The secondary objectives are comparisons of the amount of radiation exposure, ED length of stay and overall cost.
Results
and Conclusion Our low-dose protocol is readily applicable to current multi-detector computed tomography devices. If this study proves its safety and efficacy, dose-reduction without purchasing of expensive newer devices would be possible.
  • 10,418 View
  • 187 Download
Original Articles

Pulmonary | Clinical Laboratory

The clinical significance of changes in red blood cell distribution width in patients with community-acquired pneumonia
Sang-Min Lee, Jae Hyuk Lee, Kyuseok Kim, You Hwan Jo, Jungyoup Lee, Joonghee Kim, Ji Eun Hwang, Young Sang Ko, Chulmin Ha, Sujin Jang, Hyunmi Park
Clin Exp Emerg Med 2016;3(3):139-147.   Published online September 30, 2016
DOI: https://doi.org/10.15441/ceem.15.081

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The clinical significance of changes in red blood cell distribution width in patients with community-acquired pneumonia
Clin Exp Emerg Med. 2016;3(3):139-147.   Published online September 30, 2016
DOI: https://doi.org/10.15441/ceem.15.081
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The clinical significance of changes in red blood cell distribution width in patients with community-acquired pneumonia
Clin Exp Emerg Med. 2016;3(3):139-147.   Published online September 30, 2016
DOI: https://doi.org/10.15441/ceem.15.081
Close
Objective
Red cell distribution width (RDW) is associated with mortality in patients with community-acquired pneumonia (CAP). However, little is known about the effect of changes in RDW during treatment on mortality. Thus, the objective of this study was to evaluate the association between RDW changes and mortality in hospitalized patients with CAP.
Methods
Retrospective analyses were performed using medical records of patients hospitalized for CAP from April 2008 to February 2014. The abstracted laboratory values included RDW (from days one to four), clinical variables, and pneumonia severity index (PSI) scores. The ΔRDWn-1 was defined as the change in RDW calculated as: (RDWday1-RDWday-n)/RDWday1×100 (%), where ‘day n’ refers to hospital day.
Results
During the study period, a total of 1,069 patients were hospitalized for CAP. The 30-day mortality was 100/1,069 (9.4%). The median RDW at baseline was 14.1% (range, 11.1 to 30.2) and differed significantly between survivors and non-survivors (P<0.05). There were 470 patients with available serial RDW data (30-day mortality 58/470 [12.3%]). Of those, age, PSI score, blood urea nitrogen level, total protein concentration, albumin level, RDW at day 1, and the ΔRDW4-1 differed significantly between survivors and non-survivors. Multivariate Cox regression analysis showed that the significance of the relationship between ΔRDW4-1 and 30-day mortality risk remained after adjusting for age, PSI score, RDW at day 1, total protein concentration, and initial albumin level.
Conclusion
RDW change from day 1 to day 4 was an independent predictor of mortality in patients with CAP.

Citations

Citations to this article as recorded by  Crossref logo
  • Association Between the Red Cell Distribution Width‐to‐Albumin Ratio and Pediatric Community‐Acquired Pneumonia
    Zühal Örnek
    Pediatrics International.2026;[Epub]     CrossRef
  • Predicting 30-day readmissions in pneumonia patients using machine learning and residential greenness
    Seohyun Choi, Young Jae Kim, Seon Min Lee, Kwang Gi Kim
    DIGITAL HEALTH.2025;[Epub]     CrossRef
  • Association of mean RDW values and changes in RDW with in‐hospital mortality in ventilator‐associated pneumonia (VAP): Evidence from MIMIC‐IV database
    Wenbin Nan, Siqi Li, Jinfa Wan, Zhenyu Peng
    International Journal of Laboratory Hematology.2024; 46(1): 99.     CrossRef
  • Mean platelet volume (MPV) and red blood cell distribution width coefficient of variation (RDW_CV) as prognostic markers in community-acquired pneumonia in children: a cross-sectional study
    Masoud Kiani, Hengameh Shahnouri, Hasan Mahmoodi, Mohammad Pournasrollah, Hemmat Gholinia Ahangar, Mohsen Mohammadi
    Egyptian Pediatric Association Gazette.2024;[Epub]     CrossRef
  • Development and validation of a survival prediction model in elder patients with community-acquired pneumonia: a MIMIC-population-based study
    Na Li, Wenli Chu
    BMC Pulmonary Medicine.2023;[Epub]     CrossRef
  • Evaluation of red blood cell distribution width, neutrophil‐to‐lymphocyte ratio, and other hematologic parameters in canine acute pancreatitis
    Meghan M. Johnson, John C. Gicking, Deborah A. Keys
    Journal of Veterinary Emergency and Critical Care.2023; 33(5): 587.     CrossRef
  • Predictive nomogram for in-hospital mortality among older patients with intra-abdominal sepsis incorporating skeletal muscle mass
    Qiujing Li, Na Shang, Tiecheng Yang, Qian Gao, Shubin Guo
    Aging Clinical and Experimental Research.2023; 35(11): 2593.     CrossRef
  • Research Progress on Laboratory Predictors of Severe Pneumonia in Children
    瑞 杨
    Advances in Clinical Medicine.2023; 13(12): 19321.     CrossRef
  • Red Blood Cell Distribution Width and Pediatric Community-Acquired Pneumonia Disease Severity
    Jaclyn Lee, Yuwei Zhu, Derek J. Williams, Wesley H. Self, Sandra R. Arnold, Jonathan A. McCullers, Krow Ampofo, Andrew T. Pavia, Evan J. Anderson, Seema Jain, Kathryn M. Edwards, Carlos G. Grijalva
    Hospital Pediatrics.2022; 12(9): 798.     CrossRef
  • The difference in red blood cell distribution width from before to after thrombolysis as a prognostic factor in acute ischemic stroke patients: A 2-year follow-up
    Yanyan Jiang, Chuancheng Ren, Aydos Alimujiang, Yuncheng Wu, Dongya Huang, Weiting Yang
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • The diagnostic value of complete blood parameters in determining the severity of community-acquired pneumonia in children
    Deniz GÜVEN, Fatih Mehmet KIŞLAL
    Journal of Health Sciences and Medicine.2022; 5(6): 1592.     CrossRef
  • RDW-based clinical score to predict long-term survival in community-acquired pneumonia: a European derivation and validation study
    Remo Melchio, Jacopo Davide Giamello, Elisa Testa, Luis Alberto Ruiz Iturriaga, Andrea Falcetta, Cristina Serraino, Piero Riva, Christian Bracco, Leyre Serrano Fernandez, Salvatore D’Agnano, Stefano Leccardi, Massimo Porta, Luigi Maria Fenoglio
    Internal and Emergency Medicine.2021; 16(6): 1547.     CrossRef
  • Validation of Red Cell Distribution Width As a COVID-19 Severity Screening Tool
    Mandana Pouladzadeh, Mehdi Safdarian, Parastoo Moradi Choghakabodi, Fatemeh Amini, Alireza Sokooti
    Future Science OA.2021;[Epub]     CrossRef
  • The Role of Red Blood Cell Distribution Width in the Severity and Prognosis of Community-Acquired Pneumonia
    Qiang Ren, Hebing Liu, Ying Wang, Deyu Dai, Zhennan Tian, Guiwei Jiao, Xiaomin Liu, Haiyan Yin
    Canadian Respiratory Journal.2021; 2021: 1.     CrossRef
  • A literature review of severity scores for adults with influenza or community-acquired pneumonia – implications for influenza vaccines and therapeutics
    Katherine Adams, Mark W. Tenforde, Shreya Chodisetty, Benjamin Lee, Eric J. Chow, Wesley H. Self, Manish M. Patel
    Human Vaccines & Immunotherapeutics.2021; 17(12): 5460.     CrossRef
  • ΔRDW: A Novel Indicator with Predictive Value for the Diagnosis and Treatment of Multiple Diseases
    Jingsheng Wang, Qiang Xiao, Yuanmin Li
    International Journal of General Medicine.2021; Volume 14: 8667.     CrossRef
  • Initial red cell distribution width as a predictor of poor neurological outcomes in out-of-hospital cardiac arrest survivors in a prospective, multicenter observational study (the KoCARC study)
    Seon Hee Woo, Woon Jeong Lee, Dae Hee Kim, Youngsuk Cho, Gyu Chong Cho
    Scientific Reports.2020;[Epub]     CrossRef
  • Red Blood Cell Distribution Width Predicts Pulmonary Hypertension Secondary to Chronic Obstructive Pulmonary Disease
    Jie Yang, Chuanmei Liu, Lingling Li, Xiongwen Tu, Zhiwei Lu
    Canadian Respiratory Journal.2019; 2019: 1.     CrossRef
  • The relationship between level of the red cell distribution width and the outcomes of patients who acquired pneumonia from community
    Yousef A. Yousef, Mahmoud A. Manal
    Egyptian Journal of Bronchology.2019; 13(5): 738.     CrossRef
  • Severity scoring systems for pneumonia
    Otavio T. Ranzani, Leandro Utino Taniguchi, Antoni Torres
    Current Opinion in Pulmonary Medicine.2018; 24(3): 227.     CrossRef
  • High red blood cell distribution width as a marker of hospital mortality after ICU discharge: a cohort study
    Rafael Fernandez, Silvia Cano, Ignacio Catalan, Olga Rubio, Carles Subira, Jaume Masclans, Gina Rognoni, Lara Ventura, Caroline Macharete, Len Winfield, Josep Mª. Alcoverro
    Journal of Intensive Care.2018;[Epub]     CrossRef
  • New Uses for Old Biomarkers in COPD and Obstructive Sleep Apnea?
    Cristina Represas-Represas, Maribel Botana-Rial, Alberto Fernández-Villar
    Archivos de Bronconeumología (English Edition).2017; 53(3): 93.     CrossRef
  • Viejos biomarcadores, ¿nuevas utilidades en enfermedad pulmonar obstructiva crónica y apnea obstructiva del sueño?
    Cristina Represas, Maribel Botana, Alberto Fernández-Villar
    Archivos de Bronconeumología.2017; 53(3): 93.     CrossRef
  • Mortality prediction using serum biomarkers and various clinical risk scales in community-acquired pneumonia
    Min Woo Kim, Jee Yong Lim, Sang Hoon Oh
    Scandinavian Journal of Clinical and Laboratory Investigation.2017; 77(7): 486.     CrossRef
  • 16,708 View
  • 186 Download
  • 24 Web of Science
  • 24 Crossref

Critical Care

Awareness and knowledge of sepsis in the general Korean population: comparison with the awareness and knowledge of acute myocardial infarction and stroke
Minji Park, Kyuseok Kim, Jae Hyuk Lee, Changwoo Kang, You Hwan Jo, Dong Hoon Kim, Kyeong Won Kang, Soo Hoon Lee, Chanjong Park, Joonghee Kim, Heajin Chung, Hyunmi Park, Sujin Jang
Clin Exp Emerg Med 2014;1(1):41-48.   Published online September 30, 2014
DOI: https://doi.org/10.15441/ceem.14.014

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Awareness and knowledge of sepsis in the general Korean population: comparison with the awareness and knowledge of acute myocardial infarction and stroke
Clin Exp Emerg Med. 2014;1(1):41-48.   Published online September 30, 2014
DOI: https://doi.org/10.15441/ceem.14.014
Download Citation

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Awareness and knowledge of sepsis in the general Korean population: comparison with the awareness and knowledge of acute myocardial infarction and stroke
Clin Exp Emerg Med. 2014;1(1):41-48.   Published online September 30, 2014
DOI: https://doi.org/10.15441/ceem.14.014
Close
Objective

Patients with severe sepsis or septic shock require timely, aggressive management to improve their outcomes, and early presentation of patients to the hospital may also be important. Thus, public awareness about sepsis may be important for improved outcomes. However, there are no studies regarding the public awareness of sepsis in the general Korean population. Therefore, the objective of this survey was to gain insight into the public awareness of sepsis.

 Methods

Prospective paper-based and web-based surveys were issued between May and June 2013 to adults aged ≥18 years.

 Results

A total of 1,081 participants responded to the survey (394 paper-based and 687 web-based). Mean age was 38.7±11.4 years, and 541 participants (50%) were men. Of the 1,081 participants, 831 (76.9%) had heard of the term “sepsis.” Of these participants, only 295 (35%) responded correctly regarding the definition of sepsis. However, 1,019 participants (94.3%) had heard of acute myocardial infarction, and 817 of these (80%) correctly defined acute myocardial infarction. Regarding stroke, 1,047 (96.9%) had heard of stroke, and 975 of these responded (93.1%) correctly to the definition of stroke.

 Conclusion

There is poor public awareness about sepsis compared with that of acute myocardial infarction and stroke. This may limit the timely management of severe sepsis and septic shock.

Citations

Citations to this article as recorded by  Crossref logo
  • The Role of Perceived Urgency and Barriers in Using Emergency Medical Care for Sepsis: A German-Wide, Representative Survey Using Case Vignettes
    Sebastian Born, Norman Rose, Silke Piedmont, Daniel Schwarzkopf, Mathias W. Pletz, Wiltrud Abels, Konrad Reinhart, Carolin Fleischmann-Struzek
    Critical Care Medicine.2026; 54(2): 291.     CrossRef
  • Public knoweldge of sepsis in Saudi Arabia: A cross-sectional study
    Kadejh Abdulrahman Bashekah, Alla Hussain Felemban, Lubna Abdulrahman Hafiz, Abdulrahman Mauafaq Aljifri, Dalal Nasser Gaith Alsharif, Abdulaziz Ahmad Albarakati, Hind Mauafaq Aljifri, Sarah Mauafaq Aljifri, Hind Abdullah Ebrahim Abdullah, Hanan Ali Zurba
    Medicine.2025; 104(22): e42643.     CrossRef
  • Sepsis incidence, suspicion, prediction and mortality in emergency medical services: a cohort study related to the current international sepsis guideline
    Silke Piedmont, Ludwig Goldhahn, Enno Swart, Bernt-Peter Robra, Carolin Fleischmann-Struzek, Rajan Somasundaram, Wolfgang Bauer
    Infection.2024; 52(4): 1325.     CrossRef
  • Most patients with an increased risk for sepsis-related morbidity or death do not recognize sepsis as a medical emergency: results of a survey study using case vignettes
    Sebastian Born, Carolin Fleischmann-Struzek, Wiltrud Abels, Silke Piedmont, Edmund Neugebauer, Konrad Reinhart, Evjenia Toubekis, Odette Wegwarth, Daniel Schwarzkopf
    Critical Care.2023;[Epub]     CrossRef
  • Assessing Awareness and Actions Must Be Taken in Acute Myocardial Infarction: A Cross-Sectional Study on the General Population in Alahssa, Saudi Arabia
    Abdullah Almaqhawi, Abdullah Alkhalaf, Mohammed Al Qadhib, Ali M Alhashim, Norah S Alsaad, Mshari S Alqahtani, Mohammed Alqahtani, Osama F Alamri, Fatimah Buali, Ibraheem Alhusain
    Cureus.2023;[Epub]     CrossRef
  • Text-Based vs. Graphical Information Formats in Sepsis Prevention and Early Detection: A Randomized Controlled Trial on Informed Choice
    Luka Johanna Debbeler, Anne Pohrt, Carolin Fleischmann-Struzek, Daniel Schwarzkopf, Sebastian Born, Konrad Reinhart, Odette Wegwarth
    Journal of Clinical Medicine.2022; 11(13): 3659.     CrossRef
  • Public awareness and knowledge of sepsis: a cross-sectional survey of adults in Canada
    Jeanna Parsons Leigh, Rebecca Brundin-Mather, Stephana Julia Moss, Angie Nickel, Ariana Parolini, Deirdre Walsh, Blair L. Bigham, Alix J. E. Carter, Alison Fox-Robichaud, Kirsten M. Fiest
    Critical Care.2022;[Epub]     CrossRef
  • Public Awareness of Sepsis Compared to Acute Myocardial Infarction and Stroke in Jeddah, Saudi Arabia: Questionnaire Study
    Nourah Al-Orainan, Adel Mohamed EL-Shabasy, Khawlah Alamin Al-Shanqiti, Rawan Awad Al-Harbi, Hadeel Rajeh Alnashri, Raghad Ahmed Rezqallah, Alanoud Abdallah Mirghani
    Interactive Journal of Medical Research.2020; 9(2): e16195.     CrossRef
  • Korean Registry for Improving Sepsis Survival (KISS): Protocol for a Multicenter Cohort of Adult Patients with Sepsis or Septic Shock
    Jong Hun Kim, Nam Su Ku, Youn Jeong Kim, Hong Bin Kim, Hyeri Seok, Dong-Gun Lee, Jin Seo Lee, Su Jin Jeong, Jung-Hyun Choi, Jang Wook Sohn, Min Ja Kim, Dae Won Park
    Infection & Chemotherapy.2020; 52(1): 31.     CrossRef
  • Level of Knowledge on Stroke and Associated Factors: A Cross-Sectional Study at Primary Health Care Centers in Morocco
    Ahmed Kharbach, Majdouline Obtel, Abderrahmane Achbani, Youssef Bouchriti, Kenza Hassouni, Laila Lahlou, Rachid Razine
    Annals of Global Health.2020;[Epub]     CrossRef
  • Development of questionnaire on awareness and action towards symptoms and risk factors of heart attack and stroke among a Malaysian population
    Abdullah Abdulmajid Abdo Ahmed, Abdulkareem Mohammed AL-Shami, Shazia Jamshed, Abdul Rahman Fata Nahas
    BMC Public Health.2019;[Epub]     CrossRef
  • Determinants of sepsis knowledge: a representative survey of the elderly population in Germany
    Sarah Eitze, Carolin Fleischmann-Struzek, Cornelia Betsch, Konrad Reinhart
    Critical Care.2018;[Epub]     CrossRef
  • Assessment of the general public's knowledge of stroke: A cross-sectional study in Yaoundé, Cameroon
    Jobert Richie Nansseu, Cedric Paterson Atangana, Saint-Just N. Petnga, Joseph Kamtchum-Tatuene, Jean Jacques Noubiap
    Journal of the Neurological Sciences.2017; 378: 123.     CrossRef
  • Public Awareness of Sepsis Is Low in Sweden
    Lisa Mellhammar, Bertil Christensson, Adam Linder
    Open Forum Infectious Diseases.2015;[Epub]     CrossRef
  • 17,094 View
  • 166 Download
  • 14 Web of Science
  • 14 Crossref
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CEEM : Clinical and Experimental Emergency Medicine