Objective Carbon monoxide (CO) poisoning causes brain injury by hypoxia and inflammatory mechanisms. Hypoxic conditions result in increased serum phosphate concentration due to loss of polarity of the cell membrane, changes in membrane fluidity, and consequent destruction of phospholipids in the cell membrane. This study aimed to evaluate whether serum phosphate measured in the emergency department (ED) can serve as an early predictor of neurocognitive sequelae 1 month after acute CO poisoning.
Methods We included patients ≥16 years with acute CO poisoning from a cohort who were treated at a single tertiary academic hospital in Wonju, Korea, between January 2006 and May 2021. Neurocognitive outcome was assessed using the Global Deterioration Scale score; patients were classified into favorable (1–3 points) or poor (4–7 points) neurocognitive outcome groups based on this score. These two groups were compared before and after propensity score matching.
Results Data from 888 patients were analyzed. Seven hundred seventy-one patients (86.8%) were assigned to the favorable outcome group and 117 patients (13.2%) to the poor outcome group. Patients with a poor outcome had a higher mean serum phosphate level than those with a favorable outcome (3.9 mg/dL vs. 3.5 mg/dL, P=0.001). Propensity score matching yielded 85 matched patient pairs. After matching, serum phosphate level in the ED was not significantly different between the favorable and poor outcome groups (3.9 vs. 3.7 mg/dL, P=0.349).
Conclusion Serum phosphate level measured in the ED did not predict poor neurocognitive outcomes 1 month after CO poisoning.
Citations
Citations to this article as recorded by
Correlation between Carboxyhemoglobin Levels Measured by Blood Gas Analysis and by Multiwave Pulse Oximetry Jisu Yu, Juncheol Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko Journal of Personalized Medicine.2024; 14(2): 168. CrossRef
Long-term mortality of adult patients with carbon monoxide poisoning presenting to the emergency department in Korea: a population-based cohort study Sang Hwan Lee, Soo Rack Ryu, Kyung Hun Yoo, Juncheol Lee, Yongil Cho, Tae Ho Lim, Hyunggoo Kang, Jaehoon Oh, Byuk Sung Ko Acute and Critical Care.2024; 39(4): 526. CrossRef
Predicting acute brain lesions on magnetic resonance imaging in acute carbon monoxide poisoning: a multicenter prospective observational study Kyung Hun Yoo, Hyunggoo Kang, Jaehoon Oh, Tae Ho Lim, Yongil Cho, Juncheol Lee, Sang Hwan Lee, Seungkyo Jung, Won Young Kim, Chang Hwan Sohn, Byuk Sung Ko Scientific Reports.2023;[Epub] CrossRef
Objective Carbon monoxide (CO) activates intravascular neutrophils through platelet-neutrophil aggregates, which cause neutrophil degranulation. This process causes the release of myeloperoxidase (MPO), proteases, and reactive oxygen species. The MPO index (MPXI) is a newly reported inflammatory marker that reflects the MPO level within neutrophils. The MPXI in conditions associated with neutrophil activation depends on the net effect of azurophil degranulation. This study aimed to determine whether the MPXI can predict neurocognitive prognosis 1 month after acute CO poisoning.
Methods We included patients aged ≥16 years with acute CO poisoning from a cohort at a single tertiary academic hospital in Wonju, Korea, between January 2010 and May 2021. Data from 699 patients were analyzed. The neurocognitive outcome was assessed using Global Deterioration Scale scores and classified as favorable (score, 1–3 points) or poor (score, 4–7 points). The MPXI was determined within 1 hour of arrival to the emergency department.
Results Among the 699 patients, 52 (7.4%) showed poor outcomes. The median MPXI of the patients in the poor outcome group was higher than that of the favorable outcome group (0.85 vs. 0.2, P=0.189). However, a significant difference was not found between the favorable and poor outcome groups, and MPXI was not a significant variable in multivariate logistic regression.
Conclusion The MPXI evaluated in the emergency department did not differ based on neurocognitive outcome at 1 month after acute CO poisoning.
Citations
Citations to this article as recorded by
Long-term mortality of adult patients with carbon monoxide poisoning presenting to the emergency department in Korea: a population-based cohort study Sang Hwan Lee, Soo Rack Ryu, Kyung Hun Yoo, Juncheol Lee, Yongil Cho, Tae Ho Lim, Hyunggoo Kang, Jaehoon Oh, Byuk Sung Ko Acute and Critical Care.2024; 39(4): 526. CrossRef
Predicting acute brain lesions on magnetic resonance imaging in acute carbon monoxide poisoning: a multicenter prospective observational study Kyung Hun Yoo, Hyunggoo Kang, Jaehoon Oh, Tae Ho Lim, Yongil Cho, Juncheol Lee, Sang Hwan Lee, Seungkyo Jung, Won Young Kim, Chang Hwan Sohn, Byuk Sung Ko Scientific Reports.2023;[Epub] CrossRef
Objective To analyze the incidence patterns of nervous system diseases in survivors of carbon monoxide (CO) poisoning using nationwide claims data from South Korea.
Methods A national cohort was abstracted from a database that includes patients diagnosed with CO poisoning between January 2012 and December 2018. For all nervous system diseases, we investigated the frequency, pattern of incidence, effect of intensive care unit admission, and the standardized incidence ratios (SIRs) to estimate the risk of nervous system disease after CO poisoning.
Results Of 26,778 patients, 18,720 (69.9%) were diagnosed with nervous system diseases after CO poisoning. The most common disease was disorders of sleep initiation and maintenance (n=701, 3.74%), followed by tension-type headache (n=477, 2.55%) and anoxic brain injury (n=406, 2.17%). Over half of the nervous system diseases occurred within the first year after CO poisoning. The cumulative hazard ratio for nervous system diseases in patients admitted to the intensive care unit was 2.25 (95% confidence interval [CI], 2.07–2.44). Among the frequent nervous system diseases after CO poisoning, patients had a higher risk of disorders of initiating and maintaining sleep (SIR, 1.61; 95% CI, 1.52–1.71), tension-type headache (SIR, 2.41; 95% CI, 2.23–2.61), anoxic brain injury (SIR, 58.76; 95% CI, 53.95–63.88), and post-zoster neuralgia (SIR, 1.94; 95% CI, 1.70–2.20).
Conclusion Patients who experience CO poisoning are at higher risk for several nervous system diseases. Therefore, monitoring for specific nervous system diseases is important after CO poisoning within the first year.
Citations
Citations to this article as recorded by
A double-blind randomized trial of hyperbaric oxygen for persistent symptoms after brain injury Lindell K. Weaver, Rosemary Ziemnik, Kayla Deru, Antonietta A. Russo Scientific Reports.2025;[Epub] CrossRef
Machine Learning–Based Prediction of Delayed Neurologic Sequelae in Carbon Monoxide Poisoning Using Automatically Extracted MR Imaging Features Grace Yoojin Lee, Chang Hwan Sohn, Dongwon Kim, Sang-Beom Jeon, Jihye Yun, Sungwon Ham, Yoojin Nam, Jieun Yum, Won Young Kim, Namkug Kim American Journal of Neuroradiology.2025; 46(12): 2645. CrossRef
Characteristics and toxicity of burning smoke released from non-metallic materials of ships in a closed environment Jing Yang, Zhi Li, Xun Liu, Xiaomeng Ren, Jun Wu, Xinhong Xu, Xiaochen Bao, Lu Jiang, Jingjing Fang Journal of Hazardous Materials.2024; 480: 136109. CrossRef
Long-term mortality of adult patients with carbon monoxide poisoning presenting to the emergency department in Korea: a population-based cohort study Sang Hwan Lee, Soo Rack Ryu, Kyung Hun Yoo, Juncheol Lee, Yongil Cho, Tae Ho Lim, Hyunggoo Kang, Jaehoon Oh, Byuk Sung Ko Acute and Critical Care.2024; 39(4): 526. CrossRef
Prevalence of Carbon Monoxide Poisoning and Hyperbaric Oxygen Therapy in Korea: Analysis of National Claims Data in 2010–2019 Eunah Han, Gina Yu, Hye Sun Lee, Goeun Park, Sung Phil Chung Journal of Korean Medical Science.2023;[Epub] CrossRef
Predicting acute brain lesions on magnetic resonance imaging in acute carbon monoxide poisoning: a multicenter prospective observational study Kyung Hun Yoo, Hyunggoo Kang, Jaehoon Oh, Tae Ho Lim, Yongil Cho, Juncheol Lee, Sang Hwan Lee, Seungkyo Jung, Won Young Kim, Chang Hwan Sohn, Byuk Sung Ko Scientific Reports.2023;[Epub] CrossRef
Level of knowledge about carbon monoxide poisoning and its prevention among students of the Medical School of the Universidad Abierta Interamericana of the city of Rosario (Argentina) in the year 2023 Sofía Bonardi, Rodolfo Verrone Health Leadership and Quality of Life.2023; 2: 68. CrossRef
Prevalence of Acute Myocardial and Brain Toxicity in Emergency Department Patients Exposed to Carbon Monoxide Carolina Zúñiga, Luisa Fabiola Pérez Moreno, Shirley Liperguer, Verónica Torres Cerino Open Journal of Emergency Medicine.2023; 11(04): 198. CrossRef
Tips for avoiding common mistakes in out-of-hospital diagnosis of carbon monoxide poisoning G. Fucili, M. Brauzzi Journal of Anesthesia, Analgesia and Critical Care.2022;[Epub] CrossRef
Carbon Monoxide Poisoning was Associated With Lifetime Suicidal Ideation: Evidence From A Population-Based Cross-Sectional Study in Hebei Province, China Long Sun, Keqing Li, Yunshu Zhang, Lili Zhang International Journal of Public Health.2022;[Epub] CrossRef
Prognostic value of the myeloperoxidase index for early prediction of neurologic outcome in acute carbon monoxide poisoning Joong Seok Moon, Sung Hwa Kim, Yong Sung Cha Clinical and Experimental Emergency Medicine.2022; 9(3): 230. CrossRef
Serum phosphate is not an early predictor of neurocognitive outcomes in acute carbon monoxide poisoning patients Yuseon Lee, Sung Hwa Kim, Yong Sung Cha Clinical and Experimental Emergency Medicine.2022; 10(1): 74. CrossRef
Objective This study aimed to compare the diagnostic performance of cardiac biomarkers and to evaluate the optimal cut-off values for echocardiographic cardiac injury prediction in patients with carbon monoxide (CO) poisoning.
Methods This retrospective observational cohort study included adult patients with acute CO poisoning. Patients who did not undergo transthoracic echocardiography, which was used to define patients with cardiac injury (ejection fraction <55%), were excluded. The area under the curve was used to evaluate diagnostic performance for cardiac injury prediction. Mann-Whitney U, chi-square, and Fisher exact tests were used to analyze data.
Results After excluding the 27 patients who did not undergo echocardiography, 114 patients were included in the study. Fifteen (13.2%) patients had cardiac injury. The area under the curve values for the B-type natriuretic peptide, creatine kinase-myocardial band, and troponin I were 0.711 (95% confidence interval [CI], 0.527–0.895; P=0.011), 0.766 (95% CI, 0.607–0.926; P=0.001), and 0.801 (95% CI, 0.647–0.955; P<0.001), respectively, with optimal cut-off values of 330 pg/mL, 10.1 ng/mL, and 0.455 ng/mL, respectively. The sensitivity, specificity, and positive and negative predictive values of troponin I were 67%, 91%, 53%, and 95%, respectively.
Conclusion Troponin I showed the best diagnostic performance for predicting cardiac injury in patients with CO poisoning. A cut-off value of 0.455 ng/mL appeared optimal for cardiac injury prediction. However, further studies on cardiac biomarkers and other diagnostic tools in CO poisoning are needed given the low sensitivity of troponin I.
Citations
Citations to this article as recorded by
Risk stratification for myocardial injury and mortality in acute carbon monoxide poisoning: a multivariable predictive model Yongai Ling, Changsheng Ye, Xianwei Xiong, Huihua Huang, Weiguang Wang Inhalation Toxicology.2026; 38(5): 268. CrossRef
Development of a risk prediction nomogram for delayed neuropsychiatric sequelae in patients with acute carbon monoxide poisoning Ghada N. El-Sarnagawy, Fatma M. Elgazzar, Mona M. Ghonem Inhalation Toxicology.2024; 36(6): 406. CrossRef
Multiplexed SERS Detection of Serum Cardiac Markers Using Plasmonic Metasurfaces Peng Zheng, Lintong Wu, Piyush Raj, Jeong Hee Kim, Santosh Kumar Paidi, Steve Semancik, Ishan Barman Advanced Science.2024;[Epub] CrossRef
The effect of full blood count and cardiac biomarkers on prognosis in carbon monoxide poisoning in children Sevcan İpek, Ufuk Utku Güllü, Şükrü Güngör, Şeyma Demiray Irish Journal of Medical Science (1971 -).2023; 192(5): 2457. CrossRef
What is New in Eurasian Journal of Emergency Medicine-Long-term Cardiac Effect of Carbon Monoxide Poisoning İsa Kılıçaslan Eurasian Journal of Emergency Medicine.2023; 22(2): 63. CrossRef
MYOGLOBIN vs. HEMOGLOBIN BLOCKADE MODEL RELATED SMOKE GAS INHALATION - A COMPUTATIONAL ANALYSIS LUCIANA TEODORA ROTARU, RENATA MARIA VARUT, FLAVIUS TRUICU, ALINA GIRNICEANU, MARIA FORTOFOIU, CRISTIAN CONSTANTIN Journal of Science and Arts.2022; 22(3): 711. CrossRef
Prediction of troponin I and N-terminal pro-brain natriuretic peptide levels in acute carbon monoxide poisoning using advanced electrocardiogram analysis, Alexandria, Egypt Manal Hassan Abdel Aziz, Fatma Mohamed Magdy Badr El Dine, Heba Abdel Samie Mohamed Hussein, Ahmed Mokhtar Abdelazeem, Israa Mahmoud Sanad Environmental Science and Pollution Research.2021; 28(35): 48754. CrossRef
Objective Reliable biomarkers of delayed neuropsychological sequelae (DNS) after acute carbon monoxide (CO) poisoning are lacking. This study investigated the associations between potential serum markers and the development of DNS after acute CO poisoning.
Methods Retrospective chart reviews were conducted for patients diagnosed with acute CO poisoning during a 28-month period. The patients were divided into two groups according to the presence or absence of having developed DNS. Multivariate analysis was performed to identify predictors of DNS after CO poisoning.
Results Of a total of 102 patients, 10 (9.8%) developed DNS. The levels of serum osmolarity, S100B protein, and serum lactate, as well as serum anion gap, were statistically significant in univariate analysis. Multiple logistic regression analysis showed that anion gap (adjusted odds ratio [AOR], 1.36; 95% confidence interval [CI], 1.11 to 1.88), serum lactate level (AOR, 1.74; 95% CI, 1.26 to 2.75), and serum S100B protein level ([AOR, 7.02×105; 95% CI, 4.56×102 to 9.00×1010] in model 1, [AOR, 3.69×105; 95% CI, 2.49×102 to 2.71×1011] in model 2) were independently associated with DNS development.
Conclusion Based on our preliminary results, serum lactate level, serum anion gap, and serum S100B protein level in the emergency department could be informative predictors of DNS development in patients with acute CO poisoning. These markers might have the potential to improve early recognition of DNS in patients with acute CO poisoning.
Citations
Citations to this article as recorded by
Clinical characteristics and the risk factors analysis in patients with delayed encephalopathy after acute carbon monoxide poisoning Ziang Han, Sumeng Shi, Yan Zhang, Ding Yuan, Zhigao Xu, Yanxia Gao Human & Experimental Toxicology.2025;[Epub] CrossRef
Optic nerve sheath diameter measurements to predict delayed neurological sequelae after carbon monoxide poisoning Yusuf Kenan Tekin Clinical Toxicology.2024; 62(2): 88. CrossRef
Effectiveness of Initial Troponin I and Brain Natriuretic Peptide Levels as Biomarkers for Predicting Delayed Neuropsychiatric Sequelae in Patients with CO Poisoning: A Retrospective Multicenter Observational Study Myung Hyun Jung, Juncheol Lee, Jaehoon Oh, Byuk Sung Ko, Tae Ho Lim, Hyunggoo Kang, Yongil Cho, Kyung Hun Yoo, Sang Hwan Lee, Chang Hwan Sohn, Won Young Kim Journal of Personalized Medicine.2023; 13(6): 921. CrossRef
Predicting scale of delayed neuropsychiatric sequelae in patients with acute carbon monoxide poisoning: A retrospective study Shijun Yang, Huichun Liu, Qifeng Peng, Jinlan Li, Qunhui Liu The American Journal of Emergency Medicine.2022; 52: 114. CrossRef
Prognostic value of the myeloperoxidase index for early prediction of neurologic outcome in acute carbon monoxide poisoning Joong Seok Moon, Sung Hwa Kim, Yong Sung Cha Clinical and Experimental Emergency Medicine.2022; 9(3): 230. CrossRef
Serum phosphate is not an early predictor of neurocognitive outcomes in acute carbon monoxide poisoning patients Yuseon Lee, Sung Hwa Kim, Yong Sung Cha Clinical and Experimental Emergency Medicine.2022; 10(1): 74. CrossRef
Assessment of serum glucose/potassium ratio as a predictor for delayed neuropsychiatric syndrome of carbon monoxide poisoning E Demirtaş, İ Korkmaz, YK Tekin, Es Demirtaş, İ Çaltekin Human & Experimental Toxicology.2021; 40(2): 207. CrossRef
Risk factors for delayed encephalopathy following carbon monoxide poisoning: Importance of the period of inability to walk in the acute stage Yasuhiro Suzuki, Benito Soto-Blanco PLOS ONE.2021; 16(3): e0249395. CrossRef
Serum NSE and S100B protein levels for evaluating the impaired consciousness in patients with acute carbon monoxide poisoning Litao Zhang, Jing Zhao, Qingqing Hao, Xin Xu, Hu Han, Jianguo Li Medicine.2021; 100(25): e26458. CrossRef
Use of hyperbaric oxygen therapy for preventing delayed neurological sequelae in patients with carbon monoxide poisoning: A multicenter, prospective, observational study in Japan Motoki Fujita, Masaki Todani, Kotaro Kaneda, Shinya Suzuki, Shinjiro Wakai, Shota Kikuta, Satomi Sasaki, Noriyuki Hattori, Kazuyoshi Yagishita, Koji Kuwata, Ryosuke Tsuruta, Tai-Heng Chen PLOS ONE.2021; 16(6): e0253602. CrossRef
Incidence patterns of nervous system diseases after carbon monoxide poisoning: a retrospective longitudinal study in South Korea from 2012 to 2018 Bangshill Rhee, Hyuk-Hoon Kim, Sangchun Choi, Young Gi Min Clinical and Experimental Emergency Medicine.2021; 8(2): 111. CrossRef
Prediction of delayed neuropsychiatric sequelae after carbon monoxide poisoning via serial determination of serum neuron-specific enolase levels Sangun Nah, Sungwoo Choi, Gi Woon Kim, Ji Eun Moon, Young Hwan Lee, Sangsoo Han Human & Experimental Toxicology.2021; 40(12_suppl): S339. CrossRef
Does alcohol play the role of confounder or neuroprotective agent in acute carbon monoxide poisoning? Jeong Mi Moon, Byeong Jo Chun, Yong Soo Cho, Jong Goo Mun Clinical Toxicology.2020; 58(3): 161. CrossRef
S-100β in predicting the need of hyperbaric oxygen in CO-induced delayed neurological sequels Amal SAF Hafez, Ghada N El-Sarnagawy Human & Experimental Toxicology.2020; 39(5): 614. CrossRef
Clinical and Magnetic Resonance Imaging Findings of Patients with Acute Carbon Monoxide Poisoning Nezih KAVAK, Burcu DOĞAN, Hasan SULTANOĞLU, Rasime Pelin KAVAK, Meltem ÖZDEMİR Konuralp Tıp Dergisi.2020; 12(3): 443. CrossRef
Observation on promoting resuscitation in the patients with coma of acute carbon monoxide poisoning by acupuncture combined with hyperbaric oxygen Mao-li LUO, Hui-jie LI, Liang-ce MA, Yuan JIANG World Journal of Acupuncture - Moxibustion.2019; 29(2): 103. CrossRef
Objective The effect of induced hypothermia on severe acute carbon monoxide (CO) poisoning remains to be addressed further. We investigated the effect of induced hypothermia on severe acute CO poisoning.
Methods Retrospective chart review was conducted for patients who diagnosed as severe acute CO poisoning in emergency department and underwent induced hypothermia from May 2013 to May 2014. Hospital courses with critical medication and major laboratory results were investigated through the chart review.
Results Among total 227 patients with acute CO poisoning during the period of study, patients with severe acute CO poisoning were 15. All patients underwent induced hypothermia with a temperature goal 33°C. Initial and follow-up levels of S100B protein after induced hypothermia were 0.47 μg/L (interquartile range, 0.11 to 0.71) and 0.10 μg/L (interquartile range, 0.06 to 0.37), respectively (P = 0.01). The mean Glasgow Coma Scales at emergency department admission was 6.87 ± 3.36. Except 1 patient who expired after cardiopulmonary resuscitation, Glasgow Coma Scales at 30-day of hospital discharge were 15 in 10 patients (71.4%), 14 in 1 patient (7.1%), 13 in 1 patient (7.1%), and 6 in 2 patients (14.2%). Seven patients (46.7%) developed delayed neurologic sequelae. Four patients showed mild types of delayed neurologic sequelae and 3 showed moderate to severe types of delayed neurologic sequelae.
Conclusion Most of patients underwent induced hypothermia had a good recovery from severe acute CO poisoning. Therefore, induced hypothermia may be considered as a possible treatment in severe acute CO poisoning.
Citations
Citations to this article as recorded by
Clinical characteristics and the risk factors analysis in patients with delayed encephalopathy after acute carbon monoxide poisoning Ziang Han, Sumeng Shi, Yan Zhang, Ding Yuan, Zhigao Xu, Yanxia Gao Human & Experimental Toxicology.2025;[Epub] CrossRef
Correlation between Time to Hyperbaric Oxygen Therapy and Delayed Neurological Sequelae in Acute Carbon Monoxide Poisoning Patients Sungwoo Choi, Sangun Nah, Sangsoo Han Diagnostics.2024; 14(2): 186. CrossRef
Carbon Monoxide in Healthcare Monitoring Balancing Potential and Challenges in Public Health Perspective: A Narrative Review V Mounika, Indumathi K P, Sibyl Siluvai, Krishnaprakash G Cureus.2024;[Epub] CrossRef
Neurological sequelae in acute carbon monoxide poisoning: A prospective observational study with MRI data Tianhong Wang, Yanli Zhang, Youquan Gu, Jun Chen, Junqiang Lei, Shunlin Guo Acta Neurologica Scandinavica.2022; 145(5): 590. CrossRef
Therapeutic potential of gasotransmitters for cold stress-related cardiovascular disease Haijian Sun, Xiaowei Nie, Kangying Yu, Jinsong Bian Frigid Zone Medicine.2022; 2(1): 10. CrossRef
Early predictors of brain injury in patients with acute carbon monoxide poisoning and the neuroprotection of mild hypothermia Jing-Jing Zhang, Wei-Kang Bi, Yong-Mei Cheng, Ao-Chun Yue, Hui-Ping Song, Xu-Dong Zhou, Ming-Jun Bi, Wei Han, Qin Li The American Journal of Emergency Medicine.2022; 61: 18. CrossRef
Study on brain structure network of patients with delayed encephalopathy after carbon monoxide poisoning: based on diffusion tensor imaging Wenqian Jiang, Ziru Zhao, Qingyu Wu, Liang Wang, Lu Zhou, Dan Li, Laichang He, Yongming Tan La radiologia medica.2021; 126(1): 133. CrossRef
A rare case of Holmes tremor in a worker with occupational carbon monoxide poisoning Jonathan Rutchik, Rosemarie M. Bowler, Marcia H. Ratner American Journal of Industrial Medicine.2021; 64(5): 435. CrossRef
Incidence patterns of nervous system diseases after carbon monoxide poisoning: a retrospective longitudinal study in South Korea from 2012 to 2018 Bangshill Rhee, Hyuk-Hoon Kim, Sangchun Choi, Young Gi Min Clinical and Experimental Emergency Medicine.2021; 8(2): 111. CrossRef
Effects of Adjunctive Therapeutic Hypothermia Combined With Hyperbaric Oxygen Therapy in Acute Severe Carbon Monoxide Poisoning Sun Ju Kim, Stephen R. Thom, Hyun Kim, Sung Oh Hwang, Yoonsuk Lee, Eung Joo Park, Seok Jeong Lee, Yong Sung Cha Critical Care Medicine.2020; 48(8): e706. CrossRef
Targeting optimal time for hyperbaric oxygen therapy following carbon monoxide poisoning for prevention of delayed neuropsychiatric sequelae: A retrospective study Shu-Chen Liao, Yan-Chiao Mao, Kun-Ju Yang, Kuo-Cheng Wang, Li-Ying Wu, Chen-Chang Yang Journal of the Neurological Sciences.2019; 396: 187. CrossRef
The impact of hyperthermia after acute carbon monoxide poisoning on neurological sequelae JM Moon, BJ Chun, SD Lee, MH Shin Human & Experimental Toxicology.2019; 38(4): 455. CrossRef
Determination of the value of fetuin-A as a potential biomarker for early recognition of prognosis of fatality in patients with carbon monoxide poisoning Yusuf Kenan Tekin The American Journal of Emergency Medicine.2019; 37(10): 1955. CrossRef
Serum N-terminal proBNP, not troponin I, at presentation predicts long-term neurologic outcome in acute charcoal-burning carbon monoxide intoxication Jeong Mi Moon, Byeong Jo Chun, Min Ho Shin, Seung Do Lee Clinical Toxicology.2018; 56(6): 412. CrossRef
Serum neuron-specific enolase levels at presentation and long-term neurological sequelae after acute charcoal burning-induced carbon monoxide poisoning J. M. Moon, B. J. Chun, S. D. Lee, E. J. Jung Clinical Toxicology.2018; 56(8): 751. CrossRef
Clinical chameleons: an emergency medicine focused review of carbon monoxide poisoning Patrick Chow Yuen Ng, Brit Long, Alex Koyfman Internal and Emergency Medicine.2018; 13(2): 223. CrossRef
Implementation of Targeted Temperature Management in a Patient with Cerebral Arterial Gas Embolism Se Hyun Oh, Hui Dong Kang, Sang Ku Jung, Sangchun Choi Therapeutic Hypothermia and Temperature Management.2018; 8(3): 176. CrossRef
Therapeutic Aspects of Carbon Monoxide in Cardiovascular Disease Hyuk-Hoon Kim, Sangchun Choi International Journal of Molecular Sciences.2018; 19(8): 2381. CrossRef
Serum markers and development of delayed neuropsychological sequelae after acute carbon monoxide poisoning: anion gap, lactate, osmolarity, S100B protein, and interleukin-6 Hyukhoon Kim, Sangchun Choi, Eunjung Park, Eunhui Yoon, Younggi Min, Samsun Lampotang Clinical and Experimental Emergency Medicine.2018; 5(3): 185. CrossRef
Efficacy and safety of glucocorticoids combined with hyperbaric oxygen therapy in the treatment of delayed encephalopathy after acute carbon monoxide poisoning: study protocol for a randomized controlled trial Wen-ping Xiang, Hui Xue, Bao-jun Wang Asia Pacific Journal of Clinical Trials: Nervous System Diseases.2017; 2(1): 15. CrossRef
First
Prev
