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"Complications"

Original Articles

Trauma

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Frequency of posttrauma complications during hospital admission and their association with Injury Severity Score
Clin Exp Emerg Med. 2023;10(4):410-417.   Published online July 13, 2023
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Frequency of posttrauma complications during hospital admission and their association with Injury Severity Score
Clin Exp Emerg Med. 2023;10(4):410-417.   Published online July 13, 2023
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Objective
Multiple trauma is associated with a remarkable risk of in-hospital complications, which harm healthcare services and patients. This study aimed to assess the incidence of posttrauma complications, their relationship with poor outcomes, and the effect of the Injury Severity Score (ISS) on their occurrence.
Methods
This retrospective cohort study was conducted at a pair of trauma centers, between January 2020 and December 2022. All hospitalized adult patients with multiple trauma were included in this study. Multivariable logistic regression was used to identify factors related to posttrauma complications.
Results
Among 727 multiple trauma patients, 90 (12.4%) developed in-hospital complications. The most frequent complications were pneumonia (4.8%), atelectasis (3.7%), and superficial surgical site infection (2.5%). According to multivariable logistic regression, ISS, the length of stay in the intensive care unit (ICU), the length of stay in the hospital, and mortality were significantly associated with complications. The complication rate increased by 17% with every single-unit increase in ISS (adjusted odds ratio [OR], 1.17; 95% confidence interval [CI], 1.00–1.38). Per every 1-day increase in the ICU or hospital stay, the complication rate increased by 65% (adjusted OR, 1.65; 95% CI, 1.00–2.73) and 20% (adjusted OR, 1.20; 95% CI, 1.03–1.41), respectively. Posttrauma complications were also significantly more common in patients with mortality (adjusted OR, 163.30; 95% CI, 3.04–8,779.32). In multiple trauma patients with a higher ISS, the frequency, severity, and number of complications were significantly increased.
Conclusion
In-hospital complications in multiple trauma patients are frequent and associated with poor outcomes and mortality. ISS is an important factor associated with posttrauma complications.

Citations

Citations to this article as recorded by  Crossref logo
  • The prevalence and risk factors of posttraumatic stress disorder following road traffic accidents in China: A meta-analysis
    Yanna Zhou, Juanita A Haagsma, Jan Busschbach, Rong Zeng, Zhihao Yang, Jindong Ding Petersen, Xiuquan Shi
    Traffic Injury Prevention.2026; 27(5): 526.     CrossRef
  • Ventilator-Associated Pneumonia in Trauma Patients with Splenic Injuries: Does Splenectomy Increase the Risk?
    Michael Alchaer, Ricardo Fonseca, Leonardo Diaz, Marco Henriquez, Amin Deghdan, Fabiana Sanchez, Melissa Canas, Jennifer L. McCarthy, Grant Bochicchio, Jason Snyder
    Surgical Infections.2026; 27(1): 73.     CrossRef
  • Hospital-based psychological consultation relates to post-discharge treatment engagement following violent injury
    Sydney C. Timmer-Murillo, Claire M. Bird, Andrew T. Schramm, Sacha McBain, Devi Jayan, Nicholas R. Schumann, Madeline R. Marks, Timothy J. Geier
    Journal of Trauma and Acute Care Surgery.2026;[Epub]     CrossRef
  • The Impact of Non-trauma Factors on Trauma Patient Mortality and Hospital Resource Utilization: Population-Based Retrospective Review
    Mariel Javier, Ilko Luque, Jaclyn Kliewer, Nicole Yordan Lopez, David Ritchie, Beatriz Cobo Dominguez, Orlando Morejon
    The American Surgeon™.2025; 91(3): 365.     CrossRef
  • Risk Factors and Preventive Measures of Venous Thromboembolism in Trauma Patients using Trauma Embolic Scoring System: A retrospective chart review
    Eun-Ji Choi, Hyunjin Oh
    International Emergency Nursing.2025; 79: 101585.     CrossRef
  • Analysis of Trauma Severity Scores (NISS, RTS, and MGAP) in Patients Undergoing Emergency Surgery for Abdominal Trauma: An Observational Study
    Carolyny M de Oliveira, Daniel M Mauro, Ana SVB Simões, Giulia A Sakashita, Bruna M Galetti, Thais Shimokava
    Panamerican Journal of Trauma, Critical Care & Emergency Surgery.2025; 14(1): 18.     CrossRef
  • Epidemiology, risk factors, and antimicrobial resistance of nosocomial infections in the intensive care unit trauma patients: A cross-sectional study
    Bahar Darouei, Shiva Jafari, Soodabeh Rostami, Parto Nasri, Hossein Mahjoobipour, Saeed Abbasi
    Journal of Research in Medical Sciences.2025;[Epub]     CrossRef
  • Morbidity and Mortality of Trauma Patients 55 and Older: A Study of Nontrauma Risk Factors
    Mariel A. Javier, Ilko Luque, Hector Mendez, Nicole Yordán López, Marcela Ramirez, Orlando Morejón, Mark McKenney
    The American Surgeon™.2024; 90(11): 2862.     CrossRef
  • 8,226 View
  • 170 Download
  • 8 Web of Science
  • 8 Crossref

Airway

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Use of HEAVEN criteria for predicting difficult intubation in the emergency department
Clin Exp Emerg Med. 2022;9(1):29-35.   Published online March 31, 2022
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Use of HEAVEN criteria for predicting difficult intubation in the emergency department
Clin Exp Emerg Med. 2022;9(1):29-35.   Published online March 31, 2022
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Objective
Most airway prediction tools only consider anatomical factors. The HEAVEN criteria incorporate both anatomical and physiological elements, but have never been studied in the emergency department. This study aimed to evaluate the association between HEAVEN criteria and intubation difficulty.
Methods
We conducted a prospective cross-sectional study from April 1, 2020 to January 31, 2021 in the emergency department of a tertiary public hospital. All patients requiring rapid-sequence or delayed-sequence intubation were included. Patients intubated during cardiopulmonary resuscitation were excluded. We enrolled 174 patients. Study endpoints were first pass success and intubation complications.
Results
The presence of any HEAVEN criteria was associated with a decrease in the first pass success rate (odds ratio [OR], 0.10; 95% confidence interval [CI], 0.02–0.43; P < 0.01). The anatomical challenge was the only criterion associated with first pass sucess (OR, 0.13; 95% CI, 0.05– 0.29; P < 0.01), whilst other criteria (hypoxemia, extremes of size, vomit/blood/fluid, exsanguination, and neck mobility) were not (P > 0.05). All anatomical factor criteria were associated with difficult airway view (P < 0.05). Intubation complications occurred more in the presence of hypoxemia (OR, 7.44; 95% CI, 2.82–19.63; P < 0.01) and vomit/blood/fluid (OR, 5.55; 95% CI, 2.39–12.92; P < 0.01).
Conclusion
Anatomical challenge in HEAVEN criteria can predict first pass success. All anatomical factors in HEAVEN criteria could predict difficult airway view and peri-intubation hypoxemia could be used to anticipate intubation complications. More validation studies are still needed to evaluate the use of HEAVEN criteria as a predictor tool for difficult airway.

Citations

Citations to this article as recorded by  Crossref logo
  • Description of Critical Care Transport First Pass Endotracheal Intubation Failures
    Abby L. Blake, Kalle J. Fjeld, Pietra Oelke, Matthew A. Roginski, Patricia Ruth A. Atchinson
    Air Medical Journal.2026; 45(3): 208.     CrossRef
  • A Difficult-Airway Prediction Tool for Emergency Airway Management: The HEAVEN Criteria
    Kylie Prentice, Ross Fleischman
    Evidence to Action: Official Journal of MDCalc.2026;[Epub]     CrossRef
  • Superior Vena Cava Syndrome and its Anesthetic Management: A Narrative Review
    Pruthi Gegal, Sah Sarita, Taj K. Yaseen, Dey Ankita, Samagh Navneh, Paliwal Umesh Shashank, Grewal Anju
    Annals of Cardiac Anaesthesia.2026;[Epub]     CrossRef
  • A Prospective Study Evaluating Gender Differences of Serious Outcomes through Difficult Airway Physiological Score (DAPS) in the Emergency Department
    Shahan Waheed, Rida Jawed, Ahmed Raheem, Asad Iqbal Mian
    Critical Care Research and Practice.2024; 2024: 1.     CrossRef
  • Current trends in emergency airway management: a clinical review
    Sangun Nah, Yonghee Lee, Sol Ji Choi, Jeongwoo Lee, Soyun Hwang, Seongmi Lim, Inhye Lee, Young Soon Cho, Hyun Soo Chung
    Clinical and Experimental Emergency Medicine.2024; 11(3): 243.     CrossRef
  • A comprehensive audit of difficult airway trolleys in selected Victorian hospitals
    Yaodong Tang, Teresa Pham, William PL Bradley, Fiona M Brewster, David J Brewster
    Anaesthesia and Intensive Care.2024; 52(6): 407.     CrossRef
  • Torrential intraoral bleed in a mandibular arteriovenous malformation: Resuscitation under nonoperating room settings
    Ravi Chaudhary, Gaurav Jain, Deepak Kumar Arjunan, Ananda Bhattarai
    Saudi Journal of Anaesthesia.2024; 18(4): 596.     CrossRef
  • Physiologically difficult airway: How to approach the difficulty beyond anatomy
    Diana Fonseca, Maria Inês Graça, Carolina Salgueirinho, Hélder Pereira
    Trends in Anaesthesia and Critical Care.2023; 48: 101212.     CrossRef
  • 11,108 View
  • 265 Download
  • 5 Web of Science
  • 8 Crossref

Case Report

Renal & Genitourinary

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Infant with swollen penis and apparent dysuria
Clin Exp Emerg Med. 2020;7(2):136-138.   Published online June 30, 2020
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Infant with swollen penis and apparent dysuria
Clin Exp Emerg Med. 2020;7(2):136-138.   Published online June 30, 2020
Close
Circumcision is a common elective surgical procedure performed worldwide. The Plastibell ring is a plastic device placed between the penis and the foreskin to circumcise a newborn male. This device is used routinely in neonatal circumcision, but complications such as bleeding, infection, and retention may occur. This case report describes the retention of a Plastibell device in a 21-day-old male and an innovative method to remove the device using a ring cutter. Emergency physicians should be aware of ring retention as a complication of the Plastibell ring and the proposed removal technique.

Citations

Citations to this article as recorded by  Crossref logo
  • Bedside Removal of a Retained Plastibell Ring Using Handheld Electrocautery in the Emergency Department
    Benjamin H Press, Elizabeth Chu, Emily S Blum
    Cureus.2025;[Epub]     CrossRef
  • 9,296 View
  • 119 Download
  • 1 Crossref
Original Articles

Imaging | Procedures

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Usefulness of ultrasonography for the evaluation of catheter misplacement and complications after central venous catheterization
Clin Exp Emerg Med. 2018;5(2):71-75.   Published online June 29, 2018
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Usefulness of ultrasonography for the evaluation of catheter misplacement and complications after central venous catheterization
Clin Exp Emerg Med. 2018;5(2):71-75.   Published online June 29, 2018
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Objective
To assess whether ultrasonographic examination compared to chest radiography (CXR) is effective for evaluating complications after central venous catheterization.
Methods
We performed a prospective observational study. Immediately after central venous catheter insertion, we asked the radiologic department to perform a portable CXR scan. A junior and senior medical resident each performed ultrasonographic evaluation of the position of the catheter tip and complications such as pneumothorax and pleural effusion (hemothorax). We estimated the time required for ultrasound (US) and CXR.
Results
Compared to CXR, US could equivalently identify the catheter tip in the internal jugular or subclavian veins (P=1.000). Compared with CXR, US examinations conducted by junior residents could equivalently evaluate pneumothorax (P=1.000), while US examinations conducted by senior residents could also equivalently evaluate pneumothorax (P=0.557) and pleural effusion (P=0.337). The required time for US was shorter than that for CXR (P<0.001).
Conclusion
Compared to CXR, US could equivalently and more quickly identify complications such as pneumothorax or pleural effusion.

Citations

Citations to this article as recorded by  Crossref logo
  • Point-of-care ultrasound for central venous catheter confirmation and complications in the emergency department: A systematic review and meta-analysis
    Xianhua Zhu, Gang Yang, Yaling Jin, Yangtian Ye, Jiuzhou Lin, Min Tang, Lihui Chen, Weiting Chen, Xiaowei Wang
    Journal of International Medical Research.2026;[Epub]     CrossRef
  • Central venous cannulation in critically ill patients: guidelines of the Polish Society of Anaesthesiology and Intensive Therapy
    Mateusz Zawadka, Tomasz Czarnik, Ryszard Gawda, Magdalena Miłobędzka, Julia Trzebicka, Tomasz Królicki, Radosław Owczuk, Mirosław Czuczwar, Szymon Białka, Wojciech Gola, Aleksander Aszkiełowicz, Maciej Latos, Anna Włudarczyk, Wojciech Szczeklik, Zbigniew
    Anaesthesiology Intensive Therapy.2026; 58(1): 84.     CrossRef
  • Emergent Endovascular Treatment of Iatrogenous Pseudoaneurysms of the Neck Following Jugular Catheterization
    Sinan Deniz, Gizem Abaci
    Current Medical Imaging Formerly Current Medical Imaging Reviews.2023;[Epub]     CrossRef
  • Massive hemothorax following internal jugular vein catheterization under ultrasound guidance: A case report
    Hyun Kang, Soo Young Cho, Eun Ha Suk, Wan Ju, Joon Yong Choi
    World Journal of Clinical Cases.2022; 10(17): 5776.     CrossRef
  • Ultrasound to Localize the Peripherally Inserted Central Catheter Tip Position in Newborn Infants
    Xiao-Ling Ren, Hong-Lei Li, Jing Liu, Ya-Juan Chen, Man Wang, Ru-Xin Qiu
    American Journal of Perinatology.2021; 38(02): 122.     CrossRef
  • Practice Guidelines for Central Venous Access 2020

    Anesthesiology.2020; 132(1): 8.     CrossRef
  • 9,314 View
  • 174 Download
  • 6 Web of Science
  • 6 Crossref

Toxicology

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Treatment of acute carbon monoxide poisoning with induced hypothermia
Clin Exp Emerg Med. 2016;3(2):100-104.   Published online June 30, 2016
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Treatment of acute carbon monoxide poisoning with induced hypothermia
Clin Exp Emerg Med. 2016;3(2):100-104.   Published online June 30, 2016
Close
Objective
The effect of induced hypothermia on severe acute carbon monoxide (CO) poisoning remains to be addressed further. We investigated the effect of induced hypothermia on severe acute CO poisoning.
Methods
Retrospective chart review was conducted for patients who diagnosed as severe acute CO poisoning in emergency department and underwent induced hypothermia from May 2013 to May 2014. Hospital courses with critical medication and major laboratory results were investigated through the chart review.
Results
Among total 227 patients with acute CO poisoning during the period of study, patients with severe acute CO poisoning were 15. All patients underwent induced hypothermia with a temperature goal 33°C. Initial and follow-up levels of S100B protein after induced hypothermia were 0.47 μg/L (interquartile range, 0.11 to 0.71) and 0.10 μg/L (interquartile range, 0.06 to 0.37), respectively (P = 0.01). The mean Glasgow Coma Scales at emergency department admission was 6.87 ± 3.36. Except 1 patient who expired after cardiopulmonary resuscitation, Glasgow Coma Scales at 30-day of hospital discharge were 15 in 10 patients (71.4%), 14 in 1 patient (7.1%), 13 in 1 patient (7.1%), and 6 in 2 patients (14.2%). Seven patients (46.7%) developed delayed neurologic sequelae. Four patients showed mild types of delayed neurologic sequelae and 3 showed moderate to severe types of delayed neurologic sequelae.
Conclusion
Most of patients underwent induced hypothermia had a good recovery from severe acute CO poisoning. Therefore, induced hypothermia may be considered as a possible treatment in severe acute CO poisoning.

Citations

Citations to this article as recorded by  Crossref logo
  • Clinical characteristics and the risk factors analysis in patients with delayed encephalopathy after acute carbon monoxide poisoning
    Ziang Han, Sumeng Shi, Yan Zhang, Ding Yuan, Zhigao Xu, Yanxia Gao
    Human & Experimental Toxicology.2025;[Epub]     CrossRef
  • Correlation between Time to Hyperbaric Oxygen Therapy and Delayed Neurological Sequelae in Acute Carbon Monoxide Poisoning Patients
    Sungwoo Choi, Sangun Nah, Sangsoo Han
    Diagnostics.2024; 14(2): 186.     CrossRef
  • Carbon Monoxide in Healthcare Monitoring Balancing Potential and Challenges in Public Health Perspective: A Narrative Review
    V Mounika, Indumathi K P, Sibyl Siluvai, Krishnaprakash G
    Cureus.2024;[Epub]     CrossRef
  • Neurological sequelae in acute carbon monoxide poisoning: A prospective observational study with MRI data
    Tianhong Wang, Yanli Zhang, Youquan Gu, Jun Chen, Junqiang Lei, Shunlin Guo
    Acta Neurologica Scandinavica.2022; 145(5): 590.     CrossRef
  • Therapeutic potential of gasotransmitters for cold stress-related cardiovascular disease
    Haijian Sun, Xiaowei Nie, Kangying Yu, Jinsong Bian
    Frigid Zone Medicine.2022; 2(1): 10.     CrossRef
  • Early predictors of brain injury in patients with acute carbon monoxide poisoning and the neuroprotection of mild hypothermia
    Jing-Jing Zhang, Wei-Kang Bi, Yong-Mei Cheng, Ao-Chun Yue, Hui-Ping Song, Xu-Dong Zhou, Ming-Jun Bi, Wei Han, Qin Li
    The American Journal of Emergency Medicine.2022; 61: 18.     CrossRef
  • Study on brain structure network of patients with delayed encephalopathy after carbon monoxide poisoning: based on diffusion tensor imaging
    Wenqian Jiang, Ziru Zhao, Qingyu Wu, Liang Wang, Lu Zhou, Dan Li, Laichang He, Yongming Tan
    La radiologia medica.2021; 126(1): 133.     CrossRef
  • A rare case of Holmes tremor in a worker with occupational carbon monoxide poisoning
    Jonathan Rutchik, Rosemarie M. Bowler, Marcia H. Ratner
    American Journal of Industrial Medicine.2021; 64(5): 435.     CrossRef
  • Incidence patterns of nervous system diseases after carbon monoxide poisoning: a retrospective longitudinal study in South Korea from 2012 to 2018
    Bangshill Rhee, Hyuk-Hoon Kim, Sangchun Choi, Young Gi Min
    Clinical and Experimental Emergency Medicine.2021; 8(2): 111.     CrossRef
  • Effects of Adjunctive Therapeutic Hypothermia Combined With Hyperbaric Oxygen Therapy in Acute Severe Carbon Monoxide Poisoning
    Sun Ju Kim, Stephen R. Thom, Hyun Kim, Sung Oh Hwang, Yoonsuk Lee, Eung Joo Park, Seok Jeong Lee, Yong Sung Cha
    Critical Care Medicine.2020; 48(8): e706.     CrossRef
  • Targeting optimal time for hyperbaric oxygen therapy following carbon monoxide poisoning for prevention of delayed neuropsychiatric sequelae: A retrospective study
    Shu-Chen Liao, Yan-Chiao Mao, Kun-Ju Yang, Kuo-Cheng Wang, Li-Ying Wu, Chen-Chang Yang
    Journal of the Neurological Sciences.2019; 396: 187.     CrossRef
  • The impact of hyperthermia after acute carbon monoxide poisoning on neurological sequelae
    JM Moon, BJ Chun, SD Lee, MH Shin
    Human & Experimental Toxicology.2019; 38(4): 455.     CrossRef
  • Determination of the value of fetuin-A as a potential biomarker for early recognition of prognosis of fatality in patients with carbon monoxide poisoning
    Yusuf Kenan Tekin
    The American Journal of Emergency Medicine.2019; 37(10): 1955.     CrossRef
  • Serum N-terminal proBNP, not troponin I, at presentation predicts long-term neurologic outcome in acute charcoal-burning carbon monoxide intoxication
    Jeong Mi Moon, Byeong Jo Chun, Min Ho Shin, Seung Do Lee
    Clinical Toxicology.2018; 56(6): 412.     CrossRef
  • Serum neuron-specific enolase levels at presentation and long-term neurological sequelae after acute charcoal burning-induced carbon monoxide poisoning
    J. M. Moon, B. J. Chun, S. D. Lee, E. J. Jung
    Clinical Toxicology.2018; 56(8): 751.     CrossRef
  • Clinical chameleons: an emergency medicine focused review of carbon monoxide poisoning
    Patrick Chow Yuen Ng, Brit Long, Alex Koyfman
    Internal and Emergency Medicine.2018; 13(2): 223.     CrossRef
  • Implementation of Targeted Temperature Management in a Patient with Cerebral Arterial Gas Embolism
    Se Hyun Oh, Hui Dong Kang, Sang Ku Jung, Sangchun Choi
    Therapeutic Hypothermia and Temperature Management.2018; 8(3): 176.     CrossRef
  • Therapeutic Aspects of Carbon Monoxide in Cardiovascular Disease
    Hyuk-Hoon Kim, Sangchun Choi
    International Journal of Molecular Sciences.2018; 19(8): 2381.     CrossRef
  • Serum markers and development of delayed neuropsychological sequelae after acute carbon monoxide poisoning: anion gap, lactate, osmolarity, S100B protein, and interleukin-6
    Hyukhoon Kim, Sangchun Choi, Eunjung Park, Eunhui Yoon, Younggi Min, Samsun Lampotang
    Clinical and Experimental Emergency Medicine.2018; 5(3): 185.     CrossRef
  • Efficacy and safety of glucocorticoids combined with hyperbaric oxygen therapy in the treatment of delayed encephalopathy after acute carbon monoxide poisoning: study protocol for a randomized controlled trial
    Wen-ping Xiang, Hui Xue, Bao-jun Wang
    Asia Pacific Journal of Clinical Trials: Nervous System Diseases.2017; 2(1): 15.     CrossRef
  • 11,305 View
  • 140 Download
  • 21 Web of Science
  • 20 Crossref