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"Nerve block"

Brief Review

Pain Management & Sedation

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Erector spinae plane block for intractable, nonsurgical abdominal pain: a scoping review
Clin Exp Emerg Med. 2024;11(4):379-386.   Published online March 15, 2024
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Erector spinae plane block for intractable, nonsurgical abdominal pain: a scoping review
Clin Exp Emerg Med. 2024;11(4):379-386.   Published online March 15, 2024
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Abdominal pain is one of the most common presenting chief complaints in the emergency department. Erector spinae plane block (ESPB) is an ultrasound-guided nerve block with proven effectiveness in treating visceral and somatic abdominal pain. Despite the increasing popularity of ESPB, its role in the management of nonsurgical abdominal pain has not yet been characterized. Our scoping review aims to synthesize current knowledge on the safety and efficacy of ESPB in the management of patients experiencing intractable, nonsurgical abdominal pain. We searched PubMed and Scopus to evaluate the existing literature on ESPB for nonsurgical abdominal pain. A total of 14 journal articles were included: 12 case-based studies, one systematic review, and one narrative review. All cases described the successful use of ESPB in treating abdominal pain refractory to oral or intravenous analgesic medications, and no complications were reported in any cases. This scoping review provides support for the use of ESPB to manage intractable, nonsurgical abdominal pain. ESPB has demonstrated efficacy in alleviating various conditions such as functional abdominal pain, renal colic, pancreatitis, herpetic pain, and cancer-related pain. Theoretical risks such as pneumothorax, bleeding, and infection are possible, although the studies reviewed did not report such complications.

Citations

Citations to this article as recorded by  Crossref logo
  • Comparison of quadro-iliac plane block and erector spinae plane block for postoperative analgesia management after single level lumbar discectomy surgery: a randomized, double-blind, controlled, prospective, multicenter study
    Engin İhsan Turan, Büşra Otlu Bıyıkoğlu, Volkan Özen, Selçuk Alver, Tarık Umutoğlu, Oğuzhan Cücü, Serdar Çevik, Bahadır Çiftçi, Ayça Sultan Şahin
    Journal of Anesthesia.2026; 40(1): 84.     CrossRef
  • A Pilot Study Evaluating Erector Spinae Block Versus Saline For Emergency Department Patients With Ureterolithiasis
    Michael Secko, Daniel D. Singer, Gilbert Tetteh, Matthew Vitale, Benjamin Fombonne, Kristopher Bianconi, Rafael Fernandes, Andrea Gowie, Adam J. Singer
    The Journal of Emergency Medicine.2026; 83: 1.     CrossRef
  • Efficacy of an erector spinae plane block for renal colic: a systematic review and meta-analysis
    Bart Gerard Jan Candel, Laura N Visser, Ewoud ter Avest, Milan L Ridderikhof, Bas De Groot, Rens Jacobs, Saskia Weltings, Rolf H H Groenwold, Leti van Bodegom, Wilbert B van den Hout, Marleen Kemper, Markus W Hollmann
    Emergency Medicine Journal.2025; 42(5): 317.     CrossRef
  • Treatment of gastritis and gastroparesis symptoms with erector spinae plane block in the emergency department
    Richard J. Gawel, Michael Gottlieb, Frances S. Shofer, Michael Shalaby
    The American Journal of Emergency Medicine.2025; 96: 298.e1.     CrossRef
  • The evolving role of truncal fascial plane blocks in non-surgical pain therapy: a narrative review
    Yi Gu, Yifan Qin, Jin Wu
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Erector Spinae plane block for analgesia in patients with acute pancreatitis: a scoping review
    Karim Sadik, Khang Duy Ricky Le, William Keenan
    Next Research.2025; 2(4): 100874.     CrossRef
  • Ultrasound-Guided Erector Spinae Plane Block in the Emergency Department: A Treatment for Intractable Sciatica
    Carlos A Gonzalez-Cobos, Miguel J Rosa Carrasquillo, Miguel F Agrait Gonzalez
    Cureus.2024;[Epub]     CrossRef
  • 8,563 View
  • 196 Download
  • 7 Web of Science
  • 7 Crossref

Original Articles

Procedures | Pain Management & Sedation

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Femoral nerve blocks versus standard pain control for hip fractures: a retrospective comparative analysis
Clin Exp Emerg Med. 2024;11(2):181-187.   Published online January 29, 2024
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Femoral nerve blocks versus standard pain control for hip fractures: a retrospective comparative analysis
Clin Exp Emerg Med. 2024;11(2):181-187.   Published online January 29, 2024
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Objective
Pain control for hip fractures is often achieved via intravenous opioids. However, opioids can have dangerous adverse effects, including respiratory depression and delirium. Peripheral nerve blockade is an alternative option for pain control that reduces the need for opioid analgesia. The purpose of this study was to compare the use of femoral nerve blocks versus standard pain control for patients with hip fractures. Methods This retrospective study included adult patients presenting to the emergency department with isolated hip fractures between April 2021 and September 2022. The intervention group included all patients who received a femoral nerve block during this time. An equivalent number of patients who received standard pain control during that period was randomly selected to represent the control group. The primary outcome was preoperative opioid requirement, assessed by morphine milligram equivalents (MMEs). Results During the study period, 90 patients were included in each group. Mean preoperative MME was 10.3 (95% confidence interval [CI], 7.4–13.2 MME) for the intervention group and 14.0 (95% CI, 10.2–17.8 MME) for the control group (P=0.13). Patients who received a femoral nerve block also had shorter time from emergency department triage to hospital discharge (7.2 days; 95% CI, 6.2–8.0 days) than patients who received standard care (8.6 days; 95% CI, 7.210.0 days). However, this difference was not statistically significant (P=0.09). Conclusion Femoral nerve blockade is a safe and effective alternative to opioids for pain control in patients with hip fractures.

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  • Femoral Nerve Block Versus Pericapsular Nerve Group Block for Pain Management in Emergency Department Patients with Extracapsular Hip Fractures
    Kar Mun Cheong, Hua Li, Su Weng Chau, Cheng-Han Chiang, Yi-Kung Lee, Tou-Yuan Tsai
    Journal of Clinical Medicine.2026; 15(4): 1454.     CrossRef
  • Femoral Nerve Block: A Review of the Relevant Applied Anatomy, Anatomical Variations, and Procedural Considerations
    Yuqian Dai, Michael J. Montalbano, Ewarld Marshall, Marios Loukas
    Clinical Anatomy.2026;[Epub]     CrossRef
  • Ultrasound-guided fascia iliaca compartment block versus intravenous analgesia in geriatric hip fractures: a systematic review and meta-analysis of randomized trials demonstrating superior pain control
    Chang Liu, Shunyu Han, Ai Wei, Lina Yang, Mengchang Yang
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • 13,375 View
  • 161 Download
  • 4 Web of Science
  • 3 Crossref

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“Diffusion of innovations”: a feasibility study on the pericapsular nerve group block in the emergency department for hip fractures
Clin Exp Emerg Med. 2022;9(3):198-206.   Published online September 20, 2022
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“Diffusion of innovations”: a feasibility study on the pericapsular nerve group block in the emergency department for hip fractures
Clin Exp Emerg Med. 2022;9(3):198-206.   Published online September 20, 2022
Close
Objective
Hip fractures are associated with significant morbidity and mortality. Ultrasound-guided peripheral nerve blocks are a safe method to manage pain and decrease opioid usage. The pericapsular nerve group (PENG) block is a novel, potentially superior block because of its motor-sparing effects. Through training, simulation, and supervision, we aim to determine whether it is feasible to perform the PENG block in the emergency department.
Methods
Phase 1 consisted of emergency physicians attending a workshop to demonstrate ultrasound proficiency, anatomical understanding, and procedural competency using a low-fidelity model. Phase 2 consisted of a prospective, observational, feasibility study of 10 patients with hip fractures. Pain scores, side effects, and opioid usage data were collected.
Results
The median pain score at time 0 (time of block) was 9 (interquartile range [IQR], 6.5–9). The median pain score at 30 minutes was 4 (IQR, 2.0–6.8) and 3.5 (IQR, 1.0–4.8) at 4 hours. All 10 patients required narcotics prior to the initiation of the PENG block with a median dosage of 6.25 morphine milligram equivalents (MME; IQR, 4.25–7.38 MME). After the PENG block, only 30% of the patients required further narcotics with a median dosage of 0 MME (IQR, 0–0.6 MME) until operative fixation.
Conclusion
In this feasibility study, PENG blocks were safely administered by trained emergency physicians under supervision. We demonstrated data suggesting a trend of pain relief and decreased opiate requirements, and further investigation is necessary to measure efficacy.

Citations

Citations to this article as recorded by  Crossref logo
  • Pain management in the perioperative orthogeriatric setting: Recommendations of the special interest group Orthogeriatrics of the German Geriatrics Society
    Vera Smolka, Cynthia Olotu, Mirja Modreker, Corinna Drebenstedt, Patricia Ardeleanu, Ilse Gehrke
    Zeitschrift für Gerontologie und Geriatrie.2026; 59(2): 99.     CrossRef
  • Instructional design features in ultrasound‐guided regional anaesthesia simulation‐based training: a systematic review
    Pooyan Sekhavati, Tristan Wild, Ingrid D. P. C. Martinez, Pierre‐Marc Dion, Michael Woo, Reva Ramlogan, Sylvain Boet, Risa Shorr, Yuqi Gu
    Anaesthesia.2025; 80(5): 572.     CrossRef
  • Pericapsular Nerve Group Block-Augmented Analgesia vs. Conventional Opioid Analgesia for Hip Fracture Patients in the Emergency Department: A Comparative Effectiveness Study
    William Murk, Ariella Gartenberg, Jonathan Maik, Michelle A. Montenegro, Sarika Antora, Aamir Bandagi, Michael Boulay, Julie Clemmensen, Trevor Dixon, Michael Jones, Kaushal Khambhati, Nicole Leonard-Shiu, Anna Liveris, Philip O’Donnell, Anthony Scoccimar
    The Journal of Emergency Medicine.2025; 79: 232.     CrossRef
  • High-Utility Ultrasound-Guided Nerve Blocks for Emergency Department Use
    Joseph Brown, Michael Prats, Hilary Stroud, Andrew Goldsmith, Arun Nagdev
    The Journal of Emergency Medicine.2025; 79: 151.     CrossRef
  • Response to Letter to the Editor on “Pericapsular Nerve Group (PENG) Block-Augmented Analgesia vs. Conventional Opioid Analgesia for Hip Fracture Patients in the Emergency Department: A Comparative Effectiveness Study”
    William Murk, Ariella Gartenberg, Jonathan Maik, Michelle A. Montenegro, Sarika Antora, Aamir Bandagi, Michael Boulay, Julie Clemmensen, Trevor Dixon, Michael Jones, Kaushal Khambhati, Nicole Leonard-Shiu, Anna Liveris, Philip O’Donnell, Anthony Scoccimar
    The Journal of Emergency Medicine.2025; 79: 654.     CrossRef
  • Effect of early ultrasound-guided femoral nerve block on preoperative opioid consumption in emergency patients with hip fracture: a randomized trial
    Camille Gerlier, Rami Mijahed, Audrey Fels, Samir Bekka, Romain Courseau, Anne-Lyse Singh, Olivier Ganansia, Gilles Chatellier
    European Journal of Emergency Medicine.2024; 31(1): 18.     CrossRef
  • Local anesthetic systemic toxicity: awareness, recognition, and risk mitigation in the emergency department
    Michael Shalaby, Raghav Sahni, Richard Hamilton
    Clinical and Experimental Emergency Medicine.2024; 11(2): 121.     CrossRef
  • 9,131 View
  • 225 Download
  • 7 Web of Science
  • 7 Crossref
Case Reports

Pain Management & Sedation | Procedures

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Serratus anterior plane block as a bridge to outpatient management of severe rib fractures: a case report
Clin Exp Emerg Med. 2022;9(2):155-159.   Published online June 30, 2022
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Serratus anterior plane block as a bridge to outpatient management of severe rib fractures: a case report
Clin Exp Emerg Med. 2022;9(2):155-159.   Published online June 30, 2022
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Rib fractures account for a significant number of emergency department visits each year. A patient’s disposition often depends on the severity of rib fractures, comorbidities, and ability to achieve adequate analgesia. We present a 44-year-old male patient with severe pain secondary to rib fractures. The initial disposition was to admit for pain control. However, upon performing a serratus anterior plane block, patient was functionally appropriate for discharge with proper return precautions. Serratus anterior plane block is within the skillset of the emergency physician and can be used to achieve analgesia for rib fractures without the sedative and respiratory depressive effects associated with opioids.

Citations

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  • Use of fascial plane blocks for traumatic rib fractures: a scoping review
    Ahtsham U Niazi, Max Solish, Aneurin Moorthy, Faizan Niazi, Antonio Hermes Abate, Catherine Devion, Stephen Choi
    Regional Anesthesia & Pain Medicine.2026; 51(4): 414.     CrossRef
  • Ultrasound-Guided Serratus Anterior Plane Block for Acute Pain Management in Emergency Medicine: A Systematic Review
    Richard J. Gawel, Jennifer X. Hong, Erin E. Hassel, Jeffrey A. Kramer
    The Journal of Emergency Medicine.2025; 74: 13.     CrossRef
  • Validation of the 35-mm rule in traumatic pneumothorax in an Asian population
    Woo Young Nho
    Postgraduate Medicine.2024; 136(1): 60.     CrossRef
  • Efficacy and safety of the serratus anterior plane block (SAP block) for pain management in patients with multiple rib fractures in the emergency department: a retrospective study
    Sossio Serra, Domenico Pietro Santonastaso, Giuseppe Romano, Alessandro Riccardi, Stefano Geniere Nigra, Emanuele Russo, Mario Angelini, Vanni Agnoletti, Mario Guarino, Claudia Sara Cimmino, Michele Domenico Spampinato, Raffella Francesconi, Fabio De Iaco
    European Journal of Trauma and Emergency Surgery.2024; 50(6): 3177.     CrossRef
  • 8,454 View
  • 163 Download
  • 4 Web of Science
  • 4 Crossref

Procedures

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Anterior cutaneous nerve block for analgesia in anterior chest trauma: is the parasternal approach necessary?
Clin Exp Emerg Med. 2020;7(1):67-70.   Published online March 31, 2020
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Anterior cutaneous nerve block for analgesia in anterior chest trauma: is the parasternal approach necessary?
Clin Exp Emerg Med. 2020;7(1):67-70.   Published online March 31, 2020
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In recent years, several techniques of regional anesthesia have been proposed to provide analgesia to the anterior thoracic cage; notably, most of these techniques require a parasternal approach. However, in this context, the potential role of a more common and well-established technique, namely the modified pectoral nerve block (known as PECS II block), has been poorly investigated. Here, we describe a case involving a patient with bilateral anterolateral multiple rib fractures associated with sternum fracture, who was successfully treated using bilateral PECS II blocks. Our experience indicates that the PECS II block can provide excellent analgesia in cases involving anterior rib and sternum fractures. Because it is easier to perform and may be safer than other parasternal techniques, the PECS II block should be considered when providing analgesia for traumatic injuries of the anterior thorax.

Citations

Citations to this article as recorded by  Crossref logo
  • Use of fascial plane blocks for traumatic rib fractures: a scoping review
    Ahtsham U Niazi, Max Solish, Aneurin Moorthy, Faizan Niazi, Antonio Hermes Abate, Catherine Devion, Stephen Choi
    Regional Anesthesia & Pain Medicine.2026; 51(4): 414.     CrossRef
  • Differences in opioid analgesic practices between emergency medicine specialists and general practitioners: a cross-sectional study
    Mustafa Öcal
    Internal and Emergency Medicine.2026; 21(2): 549.     CrossRef
  • Ultrasound-Guided Regional Anesthesia in a Resource-Limited Hospital: Prospective Pilot Study of a Hybrid Training Program
    Jakob E Gamboa, Inge Tamm-Daniels, Roland Flores, Nancy G Sarat Diaz, Mario A Villasenor, Mitchell A Gist, Aidan B Hoie, Christopher Kurinec, Colby G Simmons
    JMIR Medical Education.2026; 12: e84181.     CrossRef
  • Efficacy and Safety of Serratus Anterior Plane Block and Erector Spinae Plane Block for Rib Fracture Pain
    Bing-Hua Lin, Hui-Min Huang, Sheng-Feng Lin
    The Clinical Journal of Pain.2026;[Epub]     CrossRef
  • When Regional Anesthesia is Mistaken for Pain Medicine: The Importance of Etiology-Driven Interventional Pain Management
    Giuliano Lo Bianco, Laura Demartini, Marco Mercieri, Michael Schatman
    Journal of Pain Research.2026; Volume 19: 1.     CrossRef
  • Evolution of simulation-based training in Italian emergency medicine residency programs: results from a national longitudinal survey (2022–2024)
    Giulia Mormando, Michela Cascio, Monica Di Cristoforo, Gianpiero Zaccaria, Bruno Barcella, Valentina Angeli, Sofia Pons, Pier Luigi Ingrassia
    Emergency Care Journal.2026;[Epub]     CrossRef
  • Evaluation of a rib fracture management pathway in an Australian tertiary trauma hospital
    Craig Morrison, Kiara Song, Tim Soon Cheok, Sean Liew, Rohen Skiba, Greg Rice, Ruurd L Jaarsma, Hidde M Kroon, D-Yin Lin
    Journal of International Medical Research.2026;[Epub]     CrossRef
  • Acute pain management of rib fractures: a narrative review
    Thomas Ulrich Bresgen, Francesco Salinaro, Bruno Barcella, Stefano Perlini, Ilenia Mascherona, Santi Di Pietro
    Injury.2025; 56(12): 112857.     CrossRef
  • Interventional Pain Procedures: A Narrative Review Focusing on Safety and Complications. Part 1 Injections for Spinal Pain
    Giuliano Lo Bianco, Andrea Tinnirello, Alfonso Papa, Vito Torrano, Gianluca Russo, Agnes Stogicza, Sebastiano Mercadante, Andrea Cortegiani, Silvia Mazzoleni, Michael E Schatman
    Journal of Pain Research.2023; Volume 16: 1637.     CrossRef
  • Current Review of Analgesia and Regional Anesthesia Practices for Rib Fracture and Chest Wall Trauma
    Paul D. Piennette, Sara Elizabeth Morris, Theresa Northern
    Current Anesthesiology Reports.2022; 12(3): 407.     CrossRef
  • Regional Anesthesia for Trauma in the Emergency Department
    Nadia Hernandez, Johanna B. de Haan
    Current Anesthesiology Reports.2022; 12(2): 240.     CrossRef
  • Bilateral PECS II Block is Associated with Decreased Opioid Consumption and Reduced Pain Scores for up to 24 hours After Minimally Invasive Repair of Pectus Excavatum (Nuss Procedure): A Retrospective Analysis
    Gokhan Sertcakacilar, Selcuk Kose
    Journal of Cardiothoracic and Vascular Anesthesia.2022; 36(10): 3833.     CrossRef
  • 8,209 View
  • 142 Download
  • 12 Web of Science
  • 12 Crossref