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"Sensitivity and specificity"

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"Sensitivity and specificity"

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Emergency Medical Services | Neurology

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Uncooperative patients suspected of acute stroke ineligible for prehospital stroke screening test by emergency medical service providers: final hospital diagnoses and characteristics
Clin Exp Emerg Med. 2023;10(2):213-223.   Published online February 14, 2023
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Uncooperative patients suspected of acute stroke ineligible for prehospital stroke screening test by emergency medical service providers: final hospital diagnoses and characteristics
Clin Exp Emerg Med. 2023;10(2):213-223.   Published online February 14, 2023
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Objective
This study investigated the hospital diagnoses and characteristics of uncooperative prehospital patients suspected of acute stroke who could not undergo a prehospital stroke screening test (PHSST).
Methods
This retrospective observational study was conducted at a single academic hospital with a regional stroke center. We analyzed three scenario-based prehospital stroke screening performances using the final hospital diagnoses: (1) a conservative approach only in patients who underwent the PHSST, (2) a real-world approach that considered all uncooperative patients as screening positive, and (3) a contrapositive approach that all uncooperative patients were considered as negative.
Results
Of the 2,836 emergency medical services (EMS)-transported adult patients who met the prehospital criteria for suspicion of acute stroke, 486 (17.1%) were uncooperative, and 570 (20.1%) had a confirmed final diagnosis of acute stroke. The diagnosis in the uncooperative group did not differ from that in the cooperative group (22.0% vs. 19.7%, P=0.246). The diagnostic performances of the PHSST in the conservative approach were as follows: 79.5% sensitivity (95% confidence interval [CI], 75.5%–83.1%), 90.2% specificity (95% CI, 88.8%–91.6%), and 0.849 area under the receiver operating characteristic curve (AUC; 95% CI, 0.829–0.868). The sensitivity and specificity were 83.3% (95% CI, 80.0%–86.3%) and 75.2% (95% CI, 73.3%–76.9%), respectively, in the real-world approach and 64.6% (95% CI, 60.5%–68.5%) and 91.9% (95% CI, 90.7%–93.0%), respectively, in the contrapositive approach. No significant difference was evident in the AUC between the real-world approach and the contrapositive approach (0.792 [95% CI, 0.775–0.810] vs. 0.782 [95% CI, 0.762–0.803], P>0.05).
Conclusion
We found overestimation (false positive) and underestimation (false negative) in the uncooperative group depending on the scenario-based EMS stroke screening policy for uncooperative prehospital patients suspected of acute stroke.

Citations

Citations to this article as recorded by  Crossref logo
  • LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p
    Rouli Dai, Wei Li, Bin Han
    Neurological Research.2026; 48(2): 229.     CrossRef
  • Impact of snoring on the risk of stroke in patients with diabetes mellitus
    Eujene Jung, U Chul Ju, Hyun Ho Ryu, Hyun Lee Kim
    Sleep and Breathing.2024; 28(6): 2675.     CrossRef
  • Epidemiology of stroke in emergency departments: a report from the National Emergency Department Information System (NEDIS) of Korea, 2018–2022
    Sung Eun Lee, Hyo Jin Kim, Young Sun Ro
    Clinical and Experimental Emergency Medicine.2023; 10(S): S48.     CrossRef
  • 7,572 View
  • 122 Download
  • 3 Web of Science
  • 3 Crossref

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Sensitivity, specificity, and predictive value of cardiac symptoms assessed by emergency medical services providers in the diagnosis of acute myocardial infarction: a multi-center observational study
Clin Exp Emerg Med. 2018;5(4):264-271.   Published online December 31, 2018
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Sensitivity, specificity, and predictive value of cardiac symptoms assessed by emergency medical services providers in the diagnosis of acute myocardial infarction: a multi-center observational study
Clin Exp Emerg Med. 2018;5(4):264-271.   Published online December 31, 2018
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Objective
For patients with acute myocardial infarction (AMI), symptoms assessed by emergency medical services (EMS) providers have a critical role in prehospital treatment decisions. The purpose of this study was to evaluate the diagnostic accuracy of EMS provider-assessed cardiac symptoms of AMI.
Methods
Patients transported by EMS to 4 study hospitals from 2008 to 2012 were included. Using EMS and administrative emergency department databases, patients were stratified according to the presence of EMS-assessed cardiac symptoms and emergency department diagnosis of AMI. Cardiac symptoms were defined as chest pain, dyspnea, palpitations, and syncope. Disproportionate stratified sampling was used, and medical records of sampled patients were reviewed to identify an actual diagnosis of AMI. Using inverse probability weighting, verification bias-corrected diagnostic performance was estimated.
Results
Overall, 92,353 patients were enrolled in the study. Of these, 13,971 (15.1%) complained of cardiac symptoms to EMS providers. A total of 775 patients were sampled for hospital record review. The sensitivity, specificity, positive predictive value, and negative predictive value of EMS provider-assessed cardiac symptoms for the final diagnosis of AMI was 73.3% (95% confidence interval [CI], 70.8 to 75.7), 85.3% (95% CI, 85.3 to 85.4), 3.9% (95% CI, 3.6 to 4.2), and 99.7% (95% CI, 99.7 to 99.8), respectively.
Conclusion
We found that EMS provider-assessed cardiac symptoms had moderate sensitivity and high specificity for diagnosis of AMI. EMS policymakers can use these data to evaluate the pertinence of specific prehospital treatment of AMI.

Citations

Citations to this article as recorded by  Crossref logo
  • Statistical Inference for Association Studies in the Presence of Binary Outcome Misclassification
    Kimberly A. Hochstedler Webb, Martin T. Wells
    Statistics in Medicine.2025;[Epub]     CrossRef
  • Structured prehospital chest pain assessment and clinical diagnostic score for prehospital identification of ST‐segment elevation myocardial infarction before an electrocardiogram
    Chun Yiu Wong, Rex Pui Kin Lam, Kent Shek Cheung, Wing Man Kwok, Tat Chi Tsang, Matthew Sik Hon Tsui, Timothy Hudson Rainer
    Hong Kong Journal of Emergency Medicine.2025;[Epub]     CrossRef
  • Increase in 9-1-1 activations for obstetric-related emergencies following the Dobbs decision in the United States
    Jonathan R Powell, Maria F Gallo, Payal Chakraborty, Colleen A Reynolds, Morgan Anderson, Parvati Singh
    American Journal of Epidemiology.2025; 194(10): 2968.     CrossRef
  • DOR TORÁCICA NA REGIÃO METROPOLITANA DA GRANDE VITÓRIA: UMA ANÁLISE DO PERFIL DOS PACIENTES ATENDIDOS PELO SAMU 192
    Júlia Ferri Leal Borges, Júlia Hubner Carvalho Venturini, Mayara Serrano de Melo Antonio, Hudson Pereira Pinto, Julianna Vaillant Louzada Oliveira, Leonardo França Vieira, Luciana Carrupt Machado Sogame, Lucas Crespo de Barros, Simone Karla Apolonio Duart
    REVISTA FOCO.2024; 17(7): e5681.     CrossRef
  • Data integration using information and communication technology for emergency medical services and systems
    Ji Hoon Kim
    Clinical and Experimental Emergency Medicine.2023; 10(2): 129.     CrossRef
  • Risk stratification of patients who present with chest pain and have normal troponins using a machine learning model
    Muhammad Shafiq, Diego Robles Mazzotti, Cheryl Gibson
    World Journal of Cardiology.2022; 14(11): 565.     CrossRef
  • Systematic Review of Clinical Decision Support Systems for Prehospital Acute Coronary Syndrome Identification
    Charles Richard Knoery, Janet Heaton, Rob Polson, Raymond Bond, Aleeha Iftikhar, Khaled Rjoob, Victoria McGilligan, Aaron Peace, Stephen James Leslie
    Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine.2020; 19(3): 119.     CrossRef
  • 9,239 View
  • 147 Download
  • 5 Web of Science
  • 7 Crossref

Imaging | Orthopedics

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New, specific ultrasonographic findings for the diagnosis of pulled elbow
Clin Exp Emerg Med. 2014;1(2):109-113.   Published online December 31, 2014
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New, specific ultrasonographic findings for the diagnosis of pulled elbow
Clin Exp Emerg Med. 2014;1(2):109-113.   Published online December 31, 2014
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Objective
Among infants and preschool children with complaint of upper extremity immobility, pulled elbow, also known as nursemaid’s elbow or radial head subluxation is the most common cause presenting to pediatric emergency departments. However, proper tools to diagnose pulled elbow remain limited. We conducted a study to determine the feasibility of ultrasonography in diagnosing pulled elbow.
Methods
Infants and preschool children presenting to an urban emergency department with the complaint of upper extremity immobility between April and July 2013 were enrolled. The following ultrasonographic information was recorded: (1) whether there was a change in the shape of the supinator muscle, (2) whether there was an annular ligament in place, and (3) whether there was an enlargement of the synovial fringe. We used the affected arms’ ultrasonographic images as the study group and opposite arms’ ultrasonographic images as the control group.
Results
When we diagnosed pulled elbow using ultrasonographic findings (i.e., the annular ligament was not in place), we found the following results: sensitivity, 64.9% (95% CI, 47.5% to 79.8%); specificity, 100.0% (95% CI, 90.5% to 100.0%); positive predictive value, 100.0% (95% CI, 85.8% to 100.0%); and negative predictive, 74.0% (95% CI, 59.7% to 85.4%).
Conclusion
A pulled elbow can easily be confirmed by ultrasonography when the annular ligament is displaced.

Citations

Citations to this article as recorded by  Crossref logo
  • The beauty of pediatric musculoskeletal ultrasound
    Elena E Drakonaki, Miraude Adriaensen, Paolo Simoni, Maria Pilar Aparisi Gomez
    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren.2025; 197(02): 172.     CrossRef
  • Irreducible (nursemaid’s) pulled elbow: a literature review of sonographic diagnostic criteria
    Philip Colucci, Olivia Tracey, Diego Jaramillo, David Scher
    Pediatric Radiology.2025; 56(2): 284.     CrossRef
  • What is the utility of point‐of‐care ultrasound for suspected pulled elbow? A single‐centre case series
    David J McCreary, Nikhil Tambe, Niall Mullen
    Journal of Paediatrics and Child Health.2024; 60(11): 698.     CrossRef
  • Ultrasound as a Diagnostic Tool for Nursemaid’s Elbow with Typical Sonographic “J Sign”
    Chun-Hin Lo, Kai-Yuan Cheng
    Formosan Journal of Musculoskeletal Disorders.2024; 15(4): 151.     CrossRef
  • The Usefulness of Dynamic Ultrasonography in Nursemaid’s Elbow: A Prospective Case Series of 13 Patients Reconsideration of the Pathophysiology of Nursemaid’s Elbow
    Chia-Che Tsai, Yi-Pin Chiang
    Journal of Pediatric Orthopaedics.2023; 43(6): e440.     CrossRef
  • Investigating the Necessity of Radiological Analysis in Pulled Elbow
    Batuhan GENCER, İhsaniye SÜER DOĞAN, Nuri Koray ÜLGEN, Mehmet Murat ARSLAN, Özgür DOĞAN
    Online Türk Sağlık Bilimleri Dergisi.2023; 8(2): 200.     CrossRef
  • A Boy With a Painful Elbow
    Jer-Ruey Chang, Tou-Yuan Tsai, Yi-Kung Lee, Su Weng Chau
    Annals of Emergency Medicine.2023; 82(5): e173.     CrossRef
  • Role of the supinator muscle in the pathophysiological mechanism of a pulled elbow
    Masahiko Kimura
    Acta Paediatrica.2022; 111(4): 756.     CrossRef
  • Ultrasound imaging in diagnostics of Monteggia lesion in children
    Martin Čepelík, Jan Hendrych, Hana Melínová, Petr Havránek, Tomáš Pešl
    Journal of Children's Orthopaedics.2022; 16(4): 262.     CrossRef
  • Two- plane point of care ultrasonography helps in the differential diagnosis of pulled elbow
    Marcell Varga, Szilvia Papp, Tamás Kassai, Tamás Bodzay, Nikoletta Gáti, Sándor Pintér
    Injury.2021; 52: S21.     CrossRef
  • Acute Ligament Injuries of the Elbow
    Diogo Guilherme Leão Edelmuth, Paulo Victor Partezani Helito, Marcos Felippe de Paula Correa, Marcelo Bordalo-Rodrigues
    Seminars in Musculoskeletal Radiology.2021; 25(04): 580.     CrossRef
  • Current Approach to the Management of Forearm and Elbow Dislocations in Children
    Michael Gottlieb, Linda I. Suleiman
    Pediatric Emergency Care.2019; 35(4): 293.     CrossRef
  • The usefulness of ultrasound and the posterior fat pad sign in pulled elbow
    Soon Hyuck Lee, Seul Gi Kim, Donghee Kwak, Seok Ha Hong, Young Keun Lee, Woo Young Jang
    Injury.2019; 50(6): 1227.     CrossRef
  • Point-of-Care Ultrasonography to Assist in the Diagnosis and Management of Subluxation of the Radial Head in Pediatric Patients: A Case Series
    Faruk Güngör, Taylan Kılıç
    The Journal of Emergency Medicine.2017; 52(5): 702.     CrossRef
  • 33,159 View
  • 197 Download
  • 15 Web of Science
  • 14 Crossref