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Resuscitation

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Variations in chest compression time, ventilation time and rescuers’ heart rate during conventional cardiopulmonary resuscitation in trained male rescuers
Clin Exp Emerg Med. 2019;6(1):31-35.   Published online February 12, 2019
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Variations in chest compression time, ventilation time and rescuers’ heart rate during conventional cardiopulmonary resuscitation in trained male rescuers
Clin Exp Emerg Med. 2019;6(1):31-35.   Published online February 12, 2019
Close
Objective
This study was conducted to determine why rescuers could maintain adequate chest compression depth for longer periods during conventional cardiopulmonary resuscitation (CPR).
Methods
Various CPR parameters, including average compression depth (ACD), average compression rate, average ventilation time (AVT), and rescuers’ heart rates were recorded in real-time when 20 health care providers performed 10 minutes of conventional CPR during a simulation experiment.
Results
The ACD was maintained above 50 mm and was not significantly different during 19 consecutive CPR cycles. The average compression rate increased from 114.9±10.0/min (2nd cycle) to 120.1±13.8/min (18th cycle) (P=0.007), and the AVT increased from 8.7±1.5 seconds (3rd cycle) to 10.1±2.6 seconds (18th cycle) (P=0.002). The rescuers’ heart rates also increased gradually for 10 min; however, they increased rapidly and were highest during the ventilation phase. Their heart rates then decreased and were lowest during the early chest compression phases of each CPR cycle. Decreases in heart rates were significant in all CPR cycles (average decrease: 14.5±4.5 beats/min, P<0.001).
Conclusion
The ACD was maintained adequately during 10 minutes of conventional CPR. However, the AVT increased significantly during the 10-minute period. The rescuers’ heart rates increased and decreased throughout all CPR cycles. These results showed that the ventilation phase might play a role as a resting period and be a reason for the maintenance of adequate chest compression depth for prolonged periods during conventional CPR.

Citations

Citations to this article as recorded by  Crossref logo
  • Influence of high altitude after a prior ascent on physical exhaustion during cardiopulmonary resuscitation: a randomised crossover alpine field experiment
    Maximilian Niederer, Katharina Tscherny, Josef Burger, Bettina Wandl, Verena Fuhrmann, Calvin L. Kienbacher, Wolfgang Schreiber, Harald Herkner, Dominik Roth, Alexander Egger
    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.2023;[Epub]     CrossRef
  • Comparison of the effects of shortening rest intervals on the quality of cardiopulmonary resuscitation, physiological parameters, and hemodynamic parameters in well-trained rescuers
    Dong Hun Kim, Sang-Min Lee, Gyun Moo Kim, Kyung Woo Lee, Seung Hyun Ko, Ye Jin Oh, Young Woo Seo, Suk Hee Lee, Tae Chang Jang
    Medicine.2021; 100(6): e24666.     CrossRef
  • Measuring the physiological impact of extreme heat on lifeguards during cardiopulmonary resuscitation. Randomized simulation study
    Roberto Barcala-Furelos, María Fernández-Méndez, Francisco Cano-Noguera, Martín Otero-Agra, Ricardo Morán-Navarro, Santiago Martínez-Isasi
    The American Journal of Emergency Medicine.2020; 38(10): 2019.     CrossRef
  • Physiological Response of Quality Cardiopulmonary Resuscitation, Crossover Trial on Mannequin in Extreme Temperature Conditions
    José Luis Martin-Conty, Begoña Polonio-López, Clara Maestre-Miquel, Alicia Mohedano-Moriano, Carlos Durantez-Fernández, Laura Mordillo-Mateos, Jesús Jurado-Palomo, Antonio Viñuela, Juan José Bernal-Jiménez, Francisco Martin-Rodríguez
    International Journal of Environmental Research and Public Health.2020; 17(16): 5835.     CrossRef
  • 9,523 View
  • 107 Download
  • 4 Web of Science
  • 4 Crossref

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Chest compression quality, exercise intensity, and energy expenditure during cardiopulmonary resuscitation using compression-to-ventilation ratios of 15:1 or 30:2 or chest compression only: a randomized, crossover manikin study
Clin Exp Emerg Med. 2016;3(3):148-157.   Published online September 30, 2016
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Chest compression quality, exercise intensity, and energy expenditure during cardiopulmonary resuscitation using compression-to-ventilation ratios of 15:1 or 30:2 or chest compression only: a randomized, crossover manikin study
Clin Exp Emerg Med. 2016;3(3):148-157.   Published online September 30, 2016
Close
Objective
Our aim was to compare the compression quality, exercise intensity, and energy expenditure in 5-minute single-rescuer cardiopulmonary resuscitation (CPR) using 15:1 or 30:2 compression-to-ventilation (C:V) ratios or chest compression only (CCO).
Methods
This was a randomized, crossover manikin study. Medical students were randomized to perform either type of CPR and do the others with intervals of at least 1 day. We measured compression quality, ratings of perceived exertion (RPE) score, heart rate, maximal oxygen uptake, and energy expenditure during CPR.
Results
Forty-seven students were recruited. Mean compression rates did not differ between the 3 groups. However, the mean percentage of adequate compressions in the CCO group was significantly lower than that of the 15:1 or 30:2 group (31.2±30.3% vs. 55.1±37.5% vs. 54.0±36.9%, respectively; P<0.001) and the difference occurred within the first minute. The RPE score in each minute and heart rate change in the CCO group was significantly higher than those of the C:V ratio groups. There was no significant difference in maximal oxygen uptake between the 3 groups. Energy expenditure in the CCO group was relatively lower than that of the 2 C:V ratio groups.
Conclusion
CPR using a 15:1 C:V ratio may provide a compression quality and exercise intensity comparable to those obtained using a 30:2 C:V ratio. An earlier decrease in compression quality and increase in RPE and heart rate could be produced by CCO CPR compared with 15:1 or 30:2 C:V ratios with relatively lower oxygen uptake and energy expenditure.

Citations

Citations to this article as recorded by  Crossref logo
  • Muscular fitness thresholds for predicting high-quality CPR: A crossover study of two compression strategies
    Chih-Hsien Chi, Chia-Lung Kao, Ming-Yuan Hong, Su-Chun Cheng, Jui-Yi Tsou
    The American Journal of Emergency Medicine.2026; 100: 148.     CrossRef
  • Effect of 24-h Shifts on Cardiopulmonary Resuscitation Performance and Fatigue: A Simulation-Based Study
    Abdul Samet Sahin, Emre Dilaver, Kaan Basar Candas, Ozgen Gonen Cekic, Muhammet Fatih Beser, Melih Imamoglu, Sinan Pasli
    The Journal of Emergency Medicine.2026; 82: 99.     CrossRef
  • Impact of Cardiopulmonary Resuscitation Health Care Workers' Physical Health Parameters on Cardiopulmonary Resuscitation Performance Quality in Simulated Manikin-Based Settings—A Systematic Review
    Prabha Prakash, Kirtana R. Nayak, Abraham S. Babu, Elsa S. Devi, Souvik Chaudhuri, Dinker R. Pai, Vimal Krishnan S
    JACEP Open.2026; 7(3): 100395.     CrossRef
  • Impact of rescuer position, arm angle, and anthropometric variables on muscle fatigue during cardiopulmonary resuscitation: an international multicentric randomized crossover simulation study
    Carla Sa-Couto, Pedro Sa-Couto, Abel Nicolau, Marc Lazarovici, Christoffer Ericsson, Pedro Vieira-Marques, Ingrid Bispo
    Resuscitation Plus.2025; 24: 100971.     CrossRef
  • Measuring the Effect of Off-Balancing Vectors on the Delivery of High-Quality CPR during Ambulance Transport: A Proof of Concept Study
    Martin A. C. Manoukian, Bryn E. Mumma, Jenny L. Wagner, Matthew T. Linvill, John S. Rose
    Prehospital Emergency Care.2024; 28(1): 107.     CrossRef
  • How Does Rescuer Fitness Affect the Quality of Prolonged Cardiopulmonary Resuscitation?
    Gabe D. Lancaster, Joshua D. Stilley, Warren D. Franke
    Prehospital Emergency Care.2022; 26(2): 195.     CrossRef
  • Effect of rotating providers on chest compression performance during simulated neonatal cardiopulmonary resuscitation
    Tavleen Sandhu, Edgardo G. Szyld, Michael P. Anderson, Birju A. Shah, Jayasree Nair
    PLOS ONE.2022; 17(3): e0265072.     CrossRef
  • Correlation between real-time heart rate and fatigue in chest compression providers during cardiopulmonary resuscitation
    Go Eun Bae, Arom Choi, Jin Ho Beom, Min Joung Kim, Hyun Soo Chung, In Kyung Min, Sung Phil Chung, Ji Hoon Kim
    Medicine.2021; 100(16): e25425.     CrossRef
  • Modified Two-Rescuer CPR With a Two-Handed Mask-Face Seal Technique Is Superior To Conventional Two-Rescuer CPR With a One-Handed Mask-Face Seal Technique
    Louis Gerber, Martin Botha, Abdullah E. Laher
    The Journal of Emergency Medicine.2021; 61(3): 252.     CrossRef
  • Quality of chest compressions during pediatric resuscitation with 15:2 and 30:2 compressions-to-ventilation ratio in a simulated scenario
    Gema Manrique, Araceli González, Maitane Iguiñiz, Ana Grau, Blanca Toledo, Miriam García, Jesús López-Herce
    Scientific Reports.2020;[Epub]     CrossRef
  • Measuring the physiological impact of extreme heat on lifeguards during cardiopulmonary resuscitation. Randomized simulation study
    Roberto Barcala-Furelos, María Fernández-Méndez, Francisco Cano-Noguera, Martín Otero-Agra, Ricardo Morán-Navarro, Santiago Martínez-Isasi
    The American Journal of Emergency Medicine.2020; 38(10): 2019.     CrossRef
  • Physiological Response of Quality Cardiopulmonary Resuscitation, Crossover Trial on Mannequin in Extreme Temperature Conditions
    José Luis Martin-Conty, Begoña Polonio-López, Clara Maestre-Miquel, Alicia Mohedano-Moriano, Carlos Durantez-Fernández, Laura Mordillo-Mateos, Jesús Jurado-Palomo, Antonio Viñuela, Juan José Bernal-Jiménez, Francisco Martin-Rodríguez
    International Journal of Environmental Research and Public Health.2020; 17(16): 5835.     CrossRef
  • How Health Habits Influence the Physiological Response During a Physical Activity in Extreme Temperatures?
    José Luis Martin-Conty, Francisco Martin-Rodríguez, Juan José Criado-Álvarez, Carlos Alberto Castillo-Sarmiento, Clara Maestre-Miquel, Alicia Mohedano-Moriano, Begoña Polonio-López, Carlos Durantez-Fernández, Miguel Ángel Castro-Villamor, Antonio Viñuela
    International Journal of Environmental Research and Public Health.2020; 17(17): 6374.     CrossRef
  • Chest Compression Duration May Be Improved When Rescuers Breathe Supplemental Oxygen
    Anna Clebone, Katherine Reis, Avery Tung, Michael OConnor, Keith J. Ruskin
    Aerospace Medicine and Human Performance.2020; 91(12): 918.     CrossRef
  • Using a smartwatch with real-time feedback improves the delivery of high-quality cardiopulmonary resuscitation by healthcare professionals
    Tsung-Chien Lu, Yao-Ting Chang, Te-Wei Ho, Yi Chen, Yi-Ting Lee, Yu-Siang Wang, Yen-Pin Chen, Chu-Lin Tsai, Matthew Huei-Ming Ma, Cheng-Chung Fang, Feipei Lai, Hendrika W. Meischke, Anne M. Turner
    Resuscitation.2019; 140: 16.     CrossRef
  • Single Ventilation during Cardiopulmonary Resuscitation Results in Better Neurological Outcomes in a Porcine Model of Cardiac Arrest
    Yong Won Kim, Hyung Il Kim, Sung Oh Hwang, Yoon Seop Kim, Gyo Jin An, Kyoung-Chul Cha
    Yonsei Medical Journal.2018; 59(10): 1232.     CrossRef
  • 14,171 View
  • 130 Download
  • 17 Web of Science
  • 16 Crossref

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The risk factors and prognostic implication of acute pulmonary edema in resuscitated cardiac arrest patients
Clin Exp Emerg Med. 2015;2(2):110-116.   Published online June 30, 2015
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The risk factors and prognostic implication of acute pulmonary edema in resuscitated cardiac arrest patients
Clin Exp Emerg Med. 2015;2(2):110-116.   Published online June 30, 2015
Close
Objective
Pulmonary edema is frequently observed after a successful resuscitation in out-of hospital cardiac arrest (OHCA) patients. Currently, its risk factors and prognostic implications are mostly unknown.
Methods
Adult OHCA patients with a presumed cardiac etiology who achieved sustained return of spontaneous circulation (ROSC) in emergency department were retrospectively analyzed. The patients were grouped according to the severity of consolidation on their initial chest X-ray (group I, no consolidation; group II, patchy consolidations; group III, consolidation involving an entire lobe; group IV, total white-out of any lung). The primary objective was to identify the risk factors of developing severe pulmonary edema (group III or IV). The secondary objective was to evaluate the association between long-term prognosis and the severity of pulmonary edema.
Results
One hundred and seven patients were included. Total duration of cardiopulmonary resuscitation (CPR) and initial pCO2 level were both independent predictors of developing severe pulmonary edema with their odds ratio (OR) being 1.02 (95% confidence interval [CI], 1.00 to 1.04; per 1 minute) and 1.04 (95% CI, 1.01 to 1.07; per 1 mmHg), respectively. The long term prognosis was significantly poor in patients with severe pulmonary edema with a OR for good outcome (6-month cerebral performance category 1 or 2) being 0.22 (95% CI, 0.06 to 0.79) in group III and 0.16 (95% CI, 0.04 to 0.63) in group IV compared to group I.
Conclusion
The duration of CPR and initial pCO2 level were both independent predictors for the development of severe pulmonary edema after resuscitation in emergency department. The severity of the pulmonary edema was significantly associated with long-term outcome.

Citations

Citations to this article as recorded by  Crossref logo
  • Rediscovery of acute lung injury in cardiac arrest: Breathing fresh air into a neglected component of the post-cardiac arrest syndrome
    Willard W. Sharp, Lin Piao
    Resuscitation.2025; 207: 110495.     CrossRef
  • Cardiac arrest related lung edema: examining the role of downtimes in transpulmonary thermodilution analysis
    Ingo Voigt, Marco Mighali, Heinrich Wieneke, Oliver Bruder
    Internal and Emergency Medicine.2024; 19(2): 501.     CrossRef
  • Super-refractory status epilepticus, rhabdomyolysis, central hyperthermia and cardiomyopathy attributable to spinal anesthesia: a case report and review of literature
    N. D.B. Ehelepola, R. M.D.C. Ranathunga, A. B. Abeysundara, H. M.R.P. Jayawardana, P. S.K. Nanayakkara
    BMC Anesthesiology.2024;[Epub]     CrossRef
  • Lung parenchymal and pleural findings on computed tomography after out-of-hospital cardiac arrest
    Maranda Newton, Jane Hall, Catherine R. Counts, Navya Gunaje, Basar Sarikaya, Vasisht Srinivasan, Kelley R.H. Branch, Nicholas J. Johnson
    Resuscitation.2024; 205: 110446.     CrossRef
  • Acute kidney injury in COVID 19 – an update on pathophysiology and management modalities
    Manoj Khokhar, Purvi Purohit, Dipayan Roy, Sojit Tomo, Ashita Gadwal, Anupama Modi, Mithu Banerjee, Praveen Sharma
    Archives of Physiology and Biochemistry.2023; 129(3): 626.     CrossRef
  • What caused this patient's cardiac arrest?
    Olga Lender
    JAAPA.2023; 36(7): 46.     CrossRef
  • Radiographic assessment of lung edema (RALE) score is associated with clinical outcomes in patients with refractory cardiogenic shock and refractory cardiac arrest after percutaneous implantation of extracorporeal life support
    Ingo Voigt, Marco Mighali, Daniela Manda, Phillip Aurich, Oliver Bruder
    Internal and Emergency Medicine.2022; 17(5): 1463.     CrossRef
  • H2O2-Responsive Antioxidant Nanoparticle Attenuates Whole Body Ischemia/Reperfusion-Induced Multi-Organ Damages
    Ruijian Li, Sang Jae Rhee, Soochan Bae, Shi Su, Chang-Sun Kang, Qingen Ke, Ye Eun Koo, Chloe Ryu, Chul Gyu Song, Dongwon Lee, Peter M. Kang
    Journal of Cardiovascular Pharmacology and Therapeutics.2021; 26(3): 279.     CrossRef
  • The effect of the head-up position on cardiopulmonary resuscitation: a systematic review and meta-analysis
    Cheng-Chieh Huang, Kuan-Chih Chen, Zih-Yang Lin, Yu-Hsuan Chou, Wen-Liang Chen, Tsung-Han Lee, Kun-Te Lin, Pei-You Hsieh, Cheng Hsu Chen, Chu-Chung Chou, Yan-Ren Lin
    Critical Care.2021;[Epub]     CrossRef
  • Radiologically and clinically diagnosed acute pulmonary oedema in critically ill patients: prevalence, patient characteristics, treatments and outcomes
    Khaled El-Khawas, Danielle Richmond, Lara Zwakman-Hessels, Salvatore L. Cutuli, Alessandro Belletti, Thummaporn Naorungroj, Hussam Abdelkarim, Natalie Yang, Rinaldo Bellomo
    Critical Care and Resuscitation.2021; 23(2): 154.     CrossRef
  • The gradient between arterial and end-tidal carbon dioxide predicts in-hospital mortality in post-cardiac arrest patient
    Yong Won Kim, Sung Oh Hwang, Hee Seung Kang, Kyoung-Chul Cha
    The American Journal of Emergency Medicine.2019; 37(1): 1.     CrossRef
  • Effect of mild hypothermia on lung injury after cardiac arrest in swine based on lung ultrasound
    Chunshuang Wu, Jiefeng Xu, Xiaohong Jin, Qijiang Chen, Zilong Li, Mao Zhang
    BMC Pulmonary Medicine.2019;[Epub]     CrossRef
  • The relationship between low survival and acute increase of tumor necrosis factor α expression in the lung in a rat model of asphyxial cardiac arrest
    Yoonsoo Park, Hyun-Jin Tae, Jeong Hwi Cho, In-Shik Kim, Taek Geun Ohk, Chan Woo Park, Joong Bum Moon, Myoung Cheol Shin, Tae-Kyeong Lee, Jae-Chul Lee, Joon Ha Park, Ji Hyeon Ahn, Seok Hoon Kang, Moo-Ho Won, Jun Hwi Cho
    Anatomy & Cell Biology.2018; 51(2): 128.     CrossRef
  • Inhibition of RHO Kinase by Fasudil Attenuates Ischemic Lung Injury After Cardiac Arrest in Rats
    Jian Wei, Peng Wang, Yi Li, Qingli Dou, Jiali Lin, Wuyuan Tao, Jinle Lin, Xuan Fu, Zitong Huang, Wenwu Zhang
    Shock.2018; 50(6): 706.     CrossRef
  • Sodium bicarbonate administration during ongoing resuscitation is associated with increased return of spontaneous circulation
    Joonghee Kim, Kyuseok Kim, Jongdae Park, You Hwan Jo, Jae Hyuk Lee, Ji Eun Hwang, Chulmin Ha, Young-sang Ko, Euigi Jung
    The American Journal of Emergency Medicine.2016; 34(2): 225.     CrossRef
  • ED crowding and the outcomes of out-of-hospital cardiac arrest
    Jiwon Kang, Joonghee Kim, You Hwan Jo, Kyuseok Kim, Jae Hyuk Lee, Taeyun Kim, Jungyoup Lee, Ji Eun Hwang, Euigi Jung
    The American Journal of Emergency Medicine.2015; 33(11): 1659.     CrossRef
  • 17,138 View
  • 137 Download
  • 20 Web of Science
  • 16 Crossref