| Underuse of rapid sequence intubation outside emergency departments: preliminary, retrospective, observational study with emergency physician insights |
Sung-Yeol Park1, Sung-Bin Chon1,2
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1Department of Emergency Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea
2Rapid Response Center, CHA Bundang Medical Center, Seongnam, Korea |
| Correspondence
Sung-Bin Chon Tel: +82-31-780-1904, Fax: +82-31-780-6125, Email: 1tim4ezra7@gmail.com |
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Received: March 30, 2024. Revised: August 31, 2024. Accepted: September 2, 2024. Published online: January 14, 2025. |
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| ABSTRACT |
Objective
Rapid sequence intubation (RSI) involves the administration of induction agents and neuromuscular blockers before endotracheal intubation (ETI). However, RSI is underutilized outside emergency departments (EDs). We compared RSI adoption rates and ETI outcomes outside and within the EDs and investigated whether RSI adoption affected ETI outcomes outside the EDs.
Methods
This retrospective study included adults who underwent emergency ETI outside the operating room at one university hospital between March 2022 and February 2023. The exclusion criteria included cardiopulmonary resuscitation, intentional RSI avoidance, and tube exchange via an introducer. The primary outcome was first-pass success rate. Secondary outcomes were multiple attempts (≥3), prolonged ETI (>5 minutes), and complications. The association between RSI adoption and outcomes outside the ED was assessed using multivariable logistic regression.
Results
A total of 490 ETI cases was included: 286 occurred outside the ED and 204 within the ED. The mean age was 68.3±14.7 years and 290 were male. Cases outside the ED received fewer RSI attempts than cases within the ED (12.6% vs. 86.8%, P<0.001). The former showed fewer incidents of first-attempt success (62.2% vs. 88.2%), more numerous multiple attempts (11.5% vs. 2.0%), longer total time of ETI (8.4±8.3 minutes vs. 2.5±2.5 minutes, P<0.001), and more frequent complications (32.2% vs. 19.6%, P=0.003). However, multivariable logistic regression revealed no significant association between RSI adoption and outcomes outside the ED: odds ratio, 1.74 (95% confidence interval [CI], 0.783–3.84), 0.167 (95% CI, 0.022–1.30), 1.04 (95% CI, 0.405–2.69), and 1.50 (95% CI, 0.664–3.40), respectively.
Conclusion
Outside the ED, RSI adoption was lower and ETI outcomes were poorer than those within the ED. However, no association was found between RSI adoption and ETI outcomes outside the ED. |
| Keywords:
Health care quality assessment; Hospital rapid response team; Intratracheal intubation; Neuromuscular blocking agent; Rapid sequence induction and intubation |
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